Med J Aust. 1988 May 2;148(9):429, 432-6.
We report here data on 1510 pregnancies that resulted from in-vitro fertilization in 12 in-vitro fertilization units in Australia and in one unit in New Zealand in the period 1979 to 1985. Live births occurred in 57.5% of all pregnancies (including preclinical abortions) and in 69.0% of clinical pregnancies. There was a high incidence of ectopic pregnancies (5.2% of clinical pregnancies) and spontaneous abortions (24.3% of intrauterine pregnancies). Of 902 viable pregnancies, 202 (22.4%) pregnancies resulted in multiple births. There were 700 infants who were born after singleton births and 438 infants who were born after multiple births. The over-all incidence of preterm delivery was 27.0%, with an incidence of 18.5% of singleton pregnancies. Low birth weight occurred in 34.8% of infants. The perinatal death rate was 47.5 deaths per 1000 births; still births accounted for three-quarters of these deaths. These findings can be used to counsel infertile couples about the risks of reproductive losses after treatment by in-vitro fertilization. National health surveys should include questions that relate to the prevalence of infertility to encourage studies of the prevention of infertility and to assess the requirements for clinical services.
我们在此报告1979年至1985年期间，澳大利亚12个体外受精单位和新西兰1个体外受精单位的1510例体外受精所致妊娠的数据。所有妊娠（包括临床前流产）的活产率为57.5%，临床妊娠的活产率为69.0%。宫外孕发生率较高（占临床妊娠的5.2%），自然流产发生率较高（占宫内妊娠的24.3%）。在902例可存活妊娠中，202例（22.4%）妊娠为多胎分娩。有700例婴儿为单胎出生后出生，438例婴儿为多胎出生后出生。早产的总体发生率为27.0%，单胎妊娠的发生率为18.5%。低出生体重儿占婴儿总数的34.8%。围产儿死亡率为每1000例出生中有47.5例死亡；死产占这些死亡的四分之三。这些研究结果可用于为不孕夫妇提供咨询，告知他们体外受精治疗后生殖损失的风险。全国健康调查应包括与不孕患病率相关的问题，以鼓励开展不孕预防研究，并评估临床服务需求。
