Ophthalmology, Addenbrooke's Hospital, Cambridge, UK
Ophthalmology, Addenbrooke's Hospital, Cambridge, UK.
BMJ Case Rep. 2021 Feb 23;14(2):e235880. doi: 10.1136/bcr-2020-235880.
In this case study, we explore a case of bilateral acute angle closure (AAC) attack detected in a 52-year-old female patient with no other ophthalmic background or predisposition to angle closure, following an increase of her regular sumatriptan dose used for migraine relief. Even though the initial presentation was misinterpreted as migraine attack, it nevertheless alerted the treating physicians to immediate cessation of the drug, allowing for the pertinent ocular symptomatology to be unveiled. Drug-induced bilateral AAC is a rare occurrence and can lead to significant ocular morbidity if not detected and treated early. Clinicians of emergency care should be aware of this uncommon association, as prompt ophthalmology input is vital. Interestingly, although it would be anticipated that people prone to angle closure attack after sumatriptan intake would exhibit symptoms after initiation of the drug, our patient suffered an attack while on long-term treatment and following dose increase.
在本病例研究中,我们探讨了一位 52 岁女性患者双侧急性闭角型青光眼(AAC)发作的病例,该患者无其他眼科背景或闭角型青光眼倾向,在偏头痛缓解常规使用舒马曲坦剂量增加后发生。尽管最初的表现被误诊为偏头痛发作,但这仍然促使治疗医生立即停止使用该药物,从而揭示了相关的眼部症状。药物诱导的双侧 AAC 较为罕见,如果不早期发现和治疗,可能会导致严重的眼部并发症。急诊医生应意识到这种不常见的关联,因为及时的眼科会诊至关重要。有趣的是,尽管人们可能预期在舒马曲坦摄入后易发生闭角型青光眼发作的人在开始用药后会出现症状,但我们的患者在长期治疗和增加剂量后出现了发作。