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闭合儿童结核病接触者管理的循环:肯尼亚西部结核病预防性治疗结局的完成情况

Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya.

作者信息

Amisi James A, Carter E Jane, Masini Enos, Szkwarko Daria

机构信息

Family Medicine, Moi University College of Health Sciences, Eldoret, Kenya.

Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.

出版信息

BMJ Open. 2021 Feb 23;11(2):e040993. doi: 10.1136/bmjopen-2020-040993.

DOI:10.1136/bmjopen-2020-040993
PMID:33622944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7907885/
Abstract

SETTING

Children especially those <5 years of age exposed to pulmonary tuberculosis (TB) are at a high risk of severe TB disease and death. Isoniazid preventive therapy (IPT) has been shown to decrease disease progression by up to 90%. Kenya, a high TB burden country experiences numerous operational challenges that limit implementation of TB preventive services. IPT completion in child contacts is not routinely reported in Kenya.

OBJECTIVE

This study aims to review the child contact management (CCM) cascade and present IPT outcomes across 10 clinics in western Kenya.

DESIGN

A retrospective chart review of programmatic data of a TB Reach-funded active, clinic-based CCM strategy.

RESULTS

Of 553 child contacts screened, 231 (42%) were reported symptomatic. 74 (13%) of the child contacts were diagnosed with active TB disease. Of those eligible for IPT, 427 (90%) initiated IPT according to TB REACH project data while 249 (58%) were recorded in the IPT register with 49 (11%) recorded as a transfer to other facilities. Of the 249 recorded in the IPT register, 205 (82%) were documented to complete therapy (48% of project initiation children).

CONCLUSION

Our evaluation shows gaps in the routine CCM care cascade related to completeness of documentation that require further programmatic monitoring and evaluation to improve CCM outcomes.

摘要

背景

儿童尤其是5岁以下接触过肺结核(TB)的儿童患严重结核病和死亡的风险很高。已证明异烟肼预防性治疗(IPT)可将疾病进展降低多达90%。肯尼亚是结核病负担较重的国家,面临诸多业务挑战,限制了结核病预防服务的实施。在肯尼亚,儿童接触者的IPT完成情况未得到常规报告。

目的

本研究旨在回顾儿童接触者管理(CCM)流程,并展示肯尼亚西部10家诊所的IPT结果。

设计

对一项由“结核病防治拓展计划”资助的、基于诊所的积极CCM策略的项目数据进行回顾性图表审查。

结果

在筛查的553名儿童接触者中,231名(42%)有症状报告。74名(13%)儿童接触者被诊断患有活动性结核病。根据“结核病防治拓展计划”项目数据,在符合IPT条件的儿童中,427名(90%)开始接受IPT,而IPT登记册中记录了249名(58%),其中49名(11%)记录为转至其他机构。在IPT登记册中记录的249名儿童中,205名(82%)有完成治疗的记录(占项目启动儿童的48%)。

结论

我们的评估显示,常规CCM护理流程在文件完整性方面存在差距,需要进一步进行项目监测和评估,以改善CCM结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5fc/7907885/b618715e7520/bmjopen-2020-040993f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5fc/7907885/b618715e7520/bmjopen-2020-040993f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5fc/7907885/b618715e7520/bmjopen-2020-040993f01.jpg

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本文引用的文献

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