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绘制高危女性的生存及HIV阳性时间的Kaplan-Meier曲线:一项队列研究

Plotting Kaplan-Meier Curves for Survival and Time to HIV Positivity among High-risk Women: A Cohort Study.

作者信息

Verma Mamtarani, Kosambiya J K

机构信息

Department of Community Medicine, Government Medical College, Surat, Gujarat, India.

出版信息

Indian J Community Med. 2020 Oct-Dec;45(4):478-482. doi: 10.4103/ijcm.IJCM_519_19. Epub 2020 Oct 28.

DOI:10.4103/ijcm.IJCM_519_19
PMID:33623205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7877404/
Abstract

INTRODUCTION

Targeted intervention (TI) project aimed to interrupt HIV transmission among highly vulnerable population and their clients.

AIMS AND OBJECTIVES

To compare survival among HIV-positive versus survival among HIV-negative women.

SUBJECTS AND METHODS STUDY DESIGN

Prospective cohort with retrospective comparison.

STUDY SETTING

Two drop in center clinics.

STUDY TOOL AND PROCESS OF DATA COLLECTION

Data were collected for 5 years from 2009 to 2014. Pretested semi-structured questionnaire was used for data collection.

RESULTS

The mean age of high-risk women was 32.48 ± 4.67 years. The mean survival among HIV-negative women was 110.62 ± 0.6 months and mean survival among HIV-positive women was 91.09 ± 7.67 months. The mean interval to death among women with sexually transmitted diseases (STDs) was 113.50 ± 1.30, whereas the mean interval to death among women with no STDs was 105.65 ± 0.76. = 0.00 by log-rank test.

CONCLUSION

Status of high-risk women according to HIV, STDs, typology, category and partner wise were found to have a significant difference in survival experience, whereas PRR positivity for syphilis, literacy, alcohol intake do not have a significant difference.

摘要

引言

针对性干预(TI)项目旨在阻断高危人群及其性伴之间的艾滋病毒传播。

目的

比较艾滋病毒阳性女性与艾滋病毒阴性女性的生存情况。

研究对象与方法 研究设计:前瞻性队列研究与回顾性比较。

研究地点

两家一站式服务中心诊所。

研究工具与数据收集过程

于2009年至2014年收集了5年的数据。采用经过预测试的半结构化问卷收集数据。

结果

高危女性的平均年龄为32.48±4.67岁。艾滋病毒阴性女性的平均生存时间为110.62±0.6个月,艾滋病毒阳性女性的平均生存时间为91.09±7.67个月。患有性传播疾病(STD)的女性的平均死亡间隔为113.50±1.30,而未患性传播疾病的女性的平均死亡间隔为105.65±0.76。经对数秩检验,P = 0.00。

结论

根据艾滋病毒、性传播疾病、类型、类别和性伴情况划分的高危女性在生存经历方面存在显著差异,而梅毒的快速血浆反应素环状卡片试验(PRR)阳性、识字率、饮酒情况则无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/7d8a597cde32/IJCM-45-478-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/ffa144a21bd7/IJCM-45-478-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/49c393fe930c/IJCM-45-478-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/dfa15c662153/IJCM-45-478-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/7d8a597cde32/IJCM-45-478-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/ffa144a21bd7/IJCM-45-478-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/49c393fe930c/IJCM-45-478-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/dfa15c662153/IJCM-45-478-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd5a/7877404/7d8a597cde32/IJCM-45-478-g004.jpg

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