飞秒激光辅助大泡性深板层角膜移植术
Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty.
作者信息
Pedrotti Emilio, Bonacci Erika, De Rossi Arianna, Bonetto Jacopo, Chierego Chiara, Fasolo Adriano, De Gregorio Alessandra, Marchini Giorgio
机构信息
Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Policlinico G.B. Rossi, Verona, 37134, Italy.
Research Unit, The Veneto Eye Bank Foundation, Venezia, 30174, Italy.
出版信息
Clin Ophthalmol. 2021 Feb 16;15:645-650. doi: 10.2147/OPTH.S294966. eCollection 2021.
PURPOSE
To determine whether type 1 big-bubble (BB) formation is influenced by the sequence of incisions created with the Victus femtosecond laser (FSL) enabled with software version 3.4 (SV 3.4) during deep anterior lamellar keratoplasty (DALK).
MATERIALS AND METHODS
Consecutive FSL-assisted DALK BB procedures were performed on 20 human donor corneas: 10 shaped by tunnel incision followed by lamellar incision (tunnel-lamellar group, TL) and 10 in the reverse order (lamellar-tunnel group, LT). The BB type was assessed by evaluating dynamic air movement during air inflation; bubble diameter and floor thickness were measured by anterior segment optical coherence tomography.
RESULTS
Overall, a type 1 BB formed in 85% of eyes: 100% in the TL group and 70% in the LT group. In the LT group, a type 2 BB formed in 2 corneas and one cornea was perforated during cannula insertion. Type 1 BB was achieved after one attempt in 90% of eyes in the TL group and in 57% in the LT group.
CONCLUSION
Shaping the tunnel before rather than after lamellar incision may be more effective for obtaining a type 1 BB by air injection.
目的
确定在深前板层角膜移植术（DALK）中，启用软件版本3.4（SV 3.4）的Victus飞秒激光（FSL）所创建的切口顺序是否会影响1型大泡（BB）的形成。
材料与方法
对20个人类供体角膜进行连续的FSL辅助DALK BB手术：10个先进行隧道切口再进行板层切口（隧道-板层组，TL），另外10个按相反顺序进行（板层-隧道组，LT）。通过评估充气过程中的动态空气流动来评估BB类型；使用眼前节光学相干断层扫描测量气泡直径和底部厚度。
结果
总体而言，85%的眼睛形成了1型BB：TL组为100%，LT组为70%。在LT组中，2只角膜形成了2型BB，1只角膜在插入套管时发生了穿孔。TL组90%的眼睛一次尝试就形成了1型BB，LT组为57%。
结论
在板层切口之前而非之后塑造隧道，对于通过空气注入获得1型BB可能更有效。
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