Dennis M, Farrell K, Hoffman H J, Hendrick E B, Becker L E, Murphy E G
Department of Psychology, Hospital for Sick Children, Toronto, Canada.
Neuropsychologia. 1988;26(1):53-65. doi: 10.1016/0028-3932(88)90030-9.
Children, adolescents, and young adults with temporal lobectomy judged the context of their encounters with a word (by deciding about its prior occurrence or familiarity) and also identified word attributes involving associative content and serial order (by indicating word meanings and reconstructing word sequences). Laterality of temporal lobectomy was important for identifying familiarity: individuals with right-sided temporal lobectomies made better judgements than those with left resections about the prior occurrence of target words, with the more successful performance depending on enhanced sensitivity to the familiarity or non-familiarity of what was heard. Identifying the attributes of an item, as contrasted with its prior occurrence, depended on aspects of temporal lobe disorder in conjunction with laterality: deficits of brain structure involving histopathology and significant tissue loss disrupted content memory; compromised brain function resulting from certain post-infantile seizures impaired memory for serial order. In the young brain after temporal lobectomy, there exists a functional dissociation between judging the familiarity of an event and identifying its attributes, a dissociation that depends, not only on laterality of surgery, but also on the structural and functional intactness of the residual brain.
接受颞叶切除术的儿童、青少年和青年判断他们遇到一个单词的情境（通过判断其先前是否出现或是否熟悉），并且还识别涉及联想内容和序列顺序的单词属性（通过指出单词含义和重建单词序列）。颞叶切除术的部位对识别熟悉度很重要：右侧颞叶切除的个体比左侧切除的个体在判断目标单词先前是否出现方面表现更好，更成功的表现取决于对所听到内容的熟悉或不熟悉的增强敏感性。与单词先前是否出现相比，识别一个项目的属性取决于颞叶疾病的方面以及部位：涉及组织病理学和显著组织损失的脑结构缺陷会破坏内容记忆；某些婴儿期后癫痫发作导致的脑功能受损会损害对序列顺序的记忆。在颞叶切除术后的年轻大脑中，判断一个事件的熟悉度和识别其属性之间存在功能分离，这种分离不仅取决于手术部位，还取决于残余大脑的结构和功能完整性。
