Akyüz Ali Rıza, Şahin Sinan, Çırakoğlu Ömer Faruk, Kul Selim, Turan Turhan, Erkan Hakan
Department of Cardiology, University of Health Sciences, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey.
Clin Exp Hypertens. 2021 May 19;43(4):368-372. doi: 10.1080/10641963.2021.1890764. Epub 2021 Feb 24.
Stiffness of large arteries has been related to cardiovascular mortality. Cardio-ankle vascular index (CAVI) is a novel marker of arterial stiffness. Herein, we aimed to study the relationship between fragmented QRS (fQRS) in electrocardiogram and CAVI.
Asymptomatic patients with fQRS and without fQRS were enrolled in the study consecutively. The fQRS complexes were analyzed in the 12-lead electrocardiogram. Arterial stiffness was assessed by using cardio ankle vascular index (CAVI). It was measured by a VaSera VS-1000 CAVI instrument.
CAVI values of the patients with fQRS was significantly higher compared to those without fQRS (8.625 (7.9-9.2) versus 6.65 (6.7-8.4) < .001). In a univariate analysis, it was revealed that there was a significant correlation between increased CAVI and fQRS, age, and epicardial fat thickness. Multiple binary logistic regression analysis revealed that age [95% confidence interval (CI): 1,068-1.214, < .001] and fQRS [95% (CI): 1.766-23.117, p: 0.005] were the independent determinants of increased CAVI values.
ECG is a widely and readily available, inexpensive, reproducible technique that can be examined by almost every physician. fQRS values in electrocardiogram may provide a significant predictive value for arterial stiffness in asymptomatic subjects.
大动脉僵硬度与心血管死亡率相关。心踝血管指数（CAVI）是动脉僵硬度的一种新型标志物。在此，我们旨在研究心电图中碎裂QRS波（fQRS）与CAVI之间的关系。
连续纳入有fQRS波和无fQRS波的无症状患者进行研究。在12导联心电图中分析fQRS波群。采用心踝血管指数（CAVI）评估动脉僵硬度。使用VaSera VS - 1000 CAVI仪器进行测量。
有fQRS波的患者的CAVI值显著高于无fQRS波的患者（8.625（7.9 - 9.2）对6.65（6.7 - 8.4），<0.001）。单因素分析显示，CAVI升高与fQRS波、年龄和心外膜脂肪厚度之间存在显著相关性。多因素二元逻辑回归分析显示，年龄[95%置信区间（CI）：1.068 - 1.214，<0.001]和fQRS波[95%（CI）：1.766 - 23.117，p：0.005]是CAVI值升高的独立决定因素。
心电图是一种广泛应用、易于获得、价格低廉且可重复的技术，几乎每位医生都能进行检查。心电图中的fQRS波值可能为无症状受试者的动脉僵硬度提供重要的预测价值。
