Gamis A S, Wasserman G S
Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108.
Pediatr Emerg Care. 1988 Mar;4(1):24-6. doi: 10.1097/00006565-198803000-00008.
The widespread presence of fingernail polish remover in the home makes the product a common source of ingestion, as evidenced by recent poison center data. Its principal component, acetone, is present in relatively high concentration. The syndrome of acetone intoxication presents as generalized central nervous system/respiratory depression, hyperglycemia, and ketosis. Despite its ubiquitous presence and high potential for severe intoxication, no reports are found describing the toxicity and supportive care following its ingestion by children. The authors present a 30-month-old patient with severe acetone intoxication secondary to fingernail polish remover ingestion. Also noted is the need to include acetone ingestion in the differential diagnosis of apparent diabetic ketoacidosis.
家庭中普遍存在指甲油去除剂，这使得该产品成为常见的摄入源，最近的中毒控制中心数据证明了这一点。其主要成分丙酮的浓度相对较高。丙酮中毒综合征表现为全身性中枢神经系统/呼吸抑制、高血糖和酮症。尽管其普遍存在且严重中毒的可能性很大，但未发现有报告描述儿童摄入后其毒性及支持治疗情况。作者介绍了一名30个月大的因摄入指甲油去除剂而导致严重丙酮中毒的患者。还指出在明显糖尿病酮症酸中毒的鉴别诊断中需要考虑丙酮摄入情况。
