Department of Dental Anesthesiology, Seoul National University Dental Hospital, Seoul, Republic of Korea.
Department of Orthodontics, Seoul National University Dental Hospital, Seoul, Republic of Korea.
Int J Med Sci. 2021 Jan 29;18(6):1432-1441. doi: 10.7150/ijms.55567. eCollection 2021.
Orthognathic surgery requires red blood cell (RBC) transfusions more frequently than other oral and maxillofacial surgeries. The purpose of this study was to identify reliable predictors for RBC transfusion during bimaxillary orthognathic surgery (BOS). This retrospective study reviewed 1,616 electronic medical records of patients who underwent BOS during a 5-year period at Seoul National University Dental Hospital. The perioperative variable data were collected from electronic medical records and analyzed by dividing patients into the two groups (non-transfusion and transfusion group). Of the 1,616 patients, 1,311 patients were excluded. The remaining 305 patients were divided into non-transfusion (NTF, n = 256) and transfusion (TF, n = 49) groups. Univariate logistic regression analysis revealed that age, body mass index, the presence of several adjunctive surgeries (including genioplasty, extraction, and mandibular angle reduction), preoperative hemoglobin (Hb) and prothrombin time, surgical time, amount of fluid infusion and blood loss, and mean pulse rate during surgery were significant factors predicting RBC transfusion. Multivariate logistic regression analysis revealed that preoperative Hb and blood loss amount during surgery were significantly related to RBC transfusion in BOS patients. Since blood loss amounts could not be measured preoperatively, we found that the independent predictor associated with RBC transfusion during BOS was a low preoperative Hb level.
正颌手术比其他口腔颌面外科手术更频繁地需要红细胞 (RBC) 输血。本研究的目的是确定双颌正颌手术 (BOS) 中 RBC 输血的可靠预测因素。这项回顾性研究回顾了首尔国立大学牙科医院在 5 年内接受 BOS 的 1616 份电子病历。围手术期变量数据从电子病历中收集,并通过将患者分为两组(非输血组和输血组)进行分析。在 1616 名患者中,有 1311 名被排除。其余 305 名患者分为非输血 (NTF,n=256) 和输血 (TF,n=49) 组。单因素逻辑回归分析显示,年龄、体重指数、是否存在多项辅助手术(包括颏成形术、拔牙和下颌角缩小术)、术前血红蛋白 (Hb) 和凝血酶原时间、手术时间、输液量和失血量以及手术期间的平均脉搏率是预测 RBC 输血的显著因素。多因素逻辑回归分析显示,术前 Hb 和手术期间的失血量与 BOS 患者的 RBC 输血显著相关。由于无法在术前测量失血量,我们发现与 BOS 期间 RBC 输血相关的独立预测因素是术前 Hb 水平低。