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双颌正颌手术中红细胞输血的预测因素:一项回顾性研究。

Predictors of Red Blood Cell Transfusion in Bimaxillary Orthognathic Surgery: A Retrospective Study.

机构信息

Department of Dental Anesthesiology, Seoul National University Dental Hospital, Seoul, Republic of Korea.

Department of Orthodontics, Seoul National University Dental Hospital, Seoul, Republic of Korea.

出版信息

Int J Med Sci. 2021 Jan 29;18(6):1432-1441. doi: 10.7150/ijms.55567. eCollection 2021.

DOI:10.7150/ijms.55567
PMID:33628100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7893559/
Abstract

Orthognathic surgery requires red blood cell (RBC) transfusions more frequently than other oral and maxillofacial surgeries. The purpose of this study was to identify reliable predictors for RBC transfusion during bimaxillary orthognathic surgery (BOS). This retrospective study reviewed 1,616 electronic medical records of patients who underwent BOS during a 5-year period at Seoul National University Dental Hospital. The perioperative variable data were collected from electronic medical records and analyzed by dividing patients into the two groups (non-transfusion and transfusion group). Of the 1,616 patients, 1,311 patients were excluded. The remaining 305 patients were divided into non-transfusion (NTF, n = 256) and transfusion (TF, n = 49) groups. Univariate logistic regression analysis revealed that age, body mass index, the presence of several adjunctive surgeries (including genioplasty, extraction, and mandibular angle reduction), preoperative hemoglobin (Hb) and prothrombin time, surgical time, amount of fluid infusion and blood loss, and mean pulse rate during surgery were significant factors predicting RBC transfusion. Multivariate logistic regression analysis revealed that preoperative Hb and blood loss amount during surgery were significantly related to RBC transfusion in BOS patients. Since blood loss amounts could not be measured preoperatively, we found that the independent predictor associated with RBC transfusion during BOS was a low preoperative Hb level.

摘要

正颌手术比其他口腔颌面外科手术更频繁地需要红细胞 (RBC) 输血。本研究的目的是确定双颌正颌手术 (BOS) 中 RBC 输血的可靠预测因素。这项回顾性研究回顾了首尔国立大学牙科医院在 5 年内接受 BOS 的 1616 份电子病历。围手术期变量数据从电子病历中收集,并通过将患者分为两组(非输血组和输血组)进行分析。在 1616 名患者中,有 1311 名被排除。其余 305 名患者分为非输血 (NTF,n=256) 和输血 (TF,n=49) 组。单因素逻辑回归分析显示,年龄、体重指数、是否存在多项辅助手术(包括颏成形术、拔牙和下颌角缩小术)、术前血红蛋白 (Hb) 和凝血酶原时间、手术时间、输液量和失血量以及手术期间的平均脉搏率是预测 RBC 输血的显著因素。多因素逻辑回归分析显示,术前 Hb 和手术期间的失血量与 BOS 患者的 RBC 输血显著相关。由于无法在术前测量失血量,我们发现与 BOS 期间 RBC 输血相关的独立预测因素是术前 Hb 水平低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7715/7893559/28c786ef29c5/ijmsv18p1432g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7715/7893559/da3b3934f58c/ijmsv18p1432g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7715/7893559/28c786ef29c5/ijmsv18p1432g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7715/7893559/da3b3934f58c/ijmsv18p1432g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7715/7893559/28c786ef29c5/ijmsv18p1432g002.jpg

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本文引用的文献

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Propofol Versus Remifentanil: Which One Is More Effective in Reducing Blood Loss During Orthognathic Surgery? A Randomized Clinical Trial.丙泊酚与瑞芬太尼:在正颌手术中哪种药物在减少失血方面更有效?一项随机临床试验。
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Perioperative red blood cell transfusion in orofacial surgery.口腔颌面外科手术中的围手术期红细胞输血
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Operative time, blood loss, hemoglobin drop, blood transfusion, and hospital stay in orthognathic surgery.
正颌外科手术的手术时间、失血量、血红蛋白下降、输血情况及住院时间。
Oral Maxillofac Surg. 2017 Jun;21(2):259-266. doi: 10.1007/s10006-017-0626-1. Epub 2017 May 2.
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Transfusion of Red Blood Cells.红细胞输注
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Effects of Hypotensive Anesthesia on Reducing Intraoperative Blood Loss, Duration of Operation, and Quality of Surgical Field During Orthognathic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.控制性低血压麻醉对正颌手术中减少术中失血、手术时间及术野质量的影响:一项随机对照试验的系统评价和Meta分析
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