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新生儿腭部自发性消退性口腔阿弗他溃疡

Spontaneously Regressing Neonatal Oral Aphthous Ulceration of the Palate.

作者信息

Madurapperuma Sandara Wayangi, Jayaweera Andra Hennadige Heshan Malinga, Jayasinghe Ruwan Duminda

机构信息

Division of Oral Medicine, Department of Oral Medicine and Periodontology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.

Department of Paediatrics, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

出版信息

Case Rep Pediatr. 2021 Feb 6;2021:6660302. doi: 10.1155/2021/6660302. eCollection 2021.

DOI:10.1155/2021/6660302
PMID:33628558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7884156/
Abstract

BACKGROUND

Neonatal oral aphthous ulceration of the palate also known as Bednar's aphthae is not an uncommon presentation. They clinically present as spontaneously regressing, shallow, and symmetrical ulcers on the posterior palate of newborns from 2 days up to 6 weeks of age. . We, herein, report a case of a one-month-old baby girl who presented with an ulcer in the posterior palate and intermittent mild fever. The patient was admitted and monitored in the ward. Haematologic investigations disclosed features of ongoing infection. Nasogastric feeding was commenced to avoid any irritation of the ulcer, and glycerine was applied on the ulcer. Antibiotic therapy was continued because of the intermittent mild fever. The lesion healed spontaneously within one week, and fever subsided afterwards. Currently, the patient is faring healthily without any complications.

CONCLUSION

Although Bednar's aphthae is not a rare presentation, clinicians are often met with a diagnostic dilemma due to the alarming clinical presentation of this condition. Therefore, it leads to overinvestigation and overtreatment. With this case report, we would like to highlight the importance of being aware of this condition to provide the patients with the appropriate treatment.

摘要

背景

新生儿腭部口腔阿弗他溃疡,也称为贝德纳口疮,并非罕见表现。临床上,它们表现为2天至6周龄新生儿腭后部自限性、浅表且对称的溃疡。在此,我们报告一例1个月大女婴,其腭后部出现溃疡并伴有间歇性低热。患者入院并在病房接受监测。血液学检查显示有持续感染的特征。开始鼻饲以避免溃疡受到任何刺激,并在溃疡处涂抹甘油。由于间歇性低热,继续使用抗生素治疗。病变在一周内自行愈合,随后发热消退。目前,患者健康状况良好,无任何并发症。

结论

尽管贝德纳口疮并非罕见表现,但由于这种疾病令人担忧的临床表现,临床医生常常面临诊断困境。因此,导致过度检查和过度治疗。通过本病例报告,我们想强调认识这种疾病以给患者提供适当治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/7884156/f68eafe57492/CRIPE2021-6660302.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/7884156/f68eafe57492/CRIPE2021-6660302.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/7884156/f68eafe57492/CRIPE2021-6660302.001.jpg

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本文引用的文献

1
Bilateral palatine ulcers in a neonate: Bednar's aphthae.
Arch Dis Child. 2018 Nov;103(11):1020. doi: 10.1136/archdischild-2017-314045. Epub 2017 Dec 8.
2
Clinical features of Bednar's aphthae in infants.婴儿贝德纳口疮的临床特征。
Korean J Pediatr. 2016 Jan;59(1):30-4. doi: 10.3345/kjp.2016.59.1.30. Epub 2016 Jan 22.
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Guideline for the diagnosis and treatment of recurrent aphthous stomatitis for dental practitioners.牙科医生复发性阿弗他口炎诊断与治疗指南
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Nipple trauma in infants? Bednar aphthae.婴儿乳头创伤?贝德纳尔口疮。
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Bednar's aphthae in neonates: incidence and associated factors.新生儿贝德尔氏口疮:发病率及相关因素。
Neonatology. 2010;98(2):208-11. doi: 10.1159/000285523. Epub 2010 Mar 25.
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Recurrent aphthous ulcers today: a review of the growing knowledge.复发性阿弗他溃疡的现状:知识进展综述
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Oral palatine ulcers of a traumatic nature in infants: Bednar's aphthae.婴儿创伤性口腔腭部溃疡:贝德纳氏口疮
Int J Pediatr Otorhinolaryngol. 1996 Mar;35(1):39-49. doi: 10.1016/0165-5876(95)01282-6.