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新冠病毒感染所致双侧下肢缺血和内脏梗死

COVID-19 Induced Bilateral Lower Limb Ischemia and Visceral Infarcts.

作者信息

Narvaneni Spandana, Fasulo Sydney M, Kumar Vinod, Singh Balraj, Sultana Yasmeen

机构信息

Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.

Hematology and Oncology, St. Joseph's Regional Medical Center, Paterson, USA.

出版信息

Cureus. 2021 Jan 19;13(1):e12784. doi: 10.7759/cureus.12784.

DOI:10.7759/cureus.12784
PMID:33628656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7890750/
Abstract

Emerging cases of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) have been associated with a variety of disorders including respiratory failure, immune reactive syndrome, multiorgan failure, and hypercoagulable states. COVID-19 induces a severe global inflammatory response which can result in endothelial damage leading to hypercoagulability. Most COVID-19 cases of hypercoagulable states reported venous thrombosis. We report here a case of a 65-year-old Hispanic male diagnosed with bilateral acute lower limb ischemia and renal infarcts secondary to a severe COVID-19 infection.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的2019冠状病毒病(COVID-19)新发病例与多种病症相关,包括呼吸衰竭、免疫反应综合征、多器官功能衰竭和高凝状态。COVID-19引发严重的全身性炎症反应,可导致内皮损伤,进而引起高凝状态。大多数报告的COVID-19高凝状态病例出现静脉血栓形成。我们在此报告一例65岁西班牙裔男性病例,该患者被诊断为双侧急性下肢缺血和严重COVID-19感染继发的肾梗死。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/090c45c3c2d9/cureus-0013-00000012784-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/1deff990045f/cureus-0013-00000012784-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/a4330f69de61/cureus-0013-00000012784-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/090c45c3c2d9/cureus-0013-00000012784-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/1deff990045f/cureus-0013-00000012784-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/a4330f69de61/cureus-0013-00000012784-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fa/7890750/090c45c3c2d9/cureus-0013-00000012784-i03.jpg

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本文引用的文献

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J Nephrol. 2021 Feb;34(1):267-268. doi: 10.1007/s40620-020-00866-2. Epub 2020 Oct 29.
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Acute Limb Ischemia in COVID-19 Disease: A Mysterious Coagulopathy.新型冠状病毒肺炎相关急性肢体缺血:一种神秘的凝血病
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Cureus. 2020 Jul 13;12(7):e9167. doi: 10.7759/cureus.9167.
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The hypercoagulable state in COVID-19: Incidence, pathophysiology, and management.新型冠状病毒肺炎中的高凝状态:发生率、病理生理学和管理。
Thromb Res. 2020 Oct;194:101-115. doi: 10.1016/j.thromres.2020.06.029. Epub 2020 Jun 20.
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Kidney Infarction in Patients With COVID-19.COVID-19 患者的肾梗死。
Am J Kidney Dis. 2020 Sep;76(3):431-435. doi: 10.1053/j.ajkd.2020.05.004. Epub 2020 May 29.
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Acute limb ischemia in patients with COVID-19 pneumonia.新型冠状病毒肺炎患者的急性肢体缺血
J Vasc Surg. 2020 Dec;72(6):1864-1872. doi: 10.1016/j.jvs.2020.04.483. Epub 2020 Apr 29.
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Incidence of thrombotic complications in critically ill ICU patients with COVID-19.COVID-19 重症监护病房危重症患者的血栓并发症发生率。
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