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颅内二级脑膜瘤寡转移至颈椎。

Intracranial Grade II Meningioma Oligometastatic to the Cervical Spine.

作者信息

Natarajan Jyotsna M, Born Donald E, Harsh Griffith, Shuer Lawrence M, Soltys Scott G

机构信息

Department of Radiation Oncology, Stanford Cancer Institute, Stanford, USA.

Department of Pathology, Stanford University School of Medicine, Stanford, USA.

出版信息

Cureus. 2021 Jan 20;13(1):e12809. doi: 10.7759/cureus.12809.

Abstract

For intracranial meningiomas that metastasize extracranially, an oligometastatic state exists that is intermediate between incurable, widely metastatic disease and non-metastatic curable disease. Similar to oligometastatic cancer, aggressive local treatment of meningioma oligometastases is warranted, as it may be curable. We present a patient with multiply recurrent intracranial meningiomas over 19 years, with a transformation from grade I to grade II histology, with oligometastatic disease to the C5 vertebral body. Three years following definitive spinal stereotactic radiosurgery, she remains without evidence of other metastatic diseases. Our case highlights the oncologic concept that metastatic meningioma need not be widely disseminated and provides the clinical rationale for aggressive local treatment of an oligometastatic meningioma.

摘要

对于发生颅外转移的颅内脑膜瘤,存在一种寡转移状态,它介于无法治愈的广泛转移性疾病和可治愈的非转移性疾病之间。与寡转移癌相似,对脑膜瘤寡转移灶进行积极的局部治疗是必要的,因为它可能是可治愈的。我们报告一名患者,其颅内脑膜瘤在19年间多次复发,组织学类型从I级转变为II级,并出现了C5椎体的寡转移疾病。在确定性脊柱立体定向放射外科治疗三年后,她仍无其他转移性疾病的证据。我们的病例突出了转移性脑膜瘤不一定广泛播散的肿瘤学概念,并为积极局部治疗寡转移脑膜瘤提供了临床依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f962/7894379/66736d64c172/cureus-0013-00000012809-i01.jpg

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