Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Western New England University, Springfield, USA.
Biomed Res Int. 2021 Feb 15;2021:8830606. doi: 10.1155/2021/8830606. eCollection 2021.
There is a lack of data on drug-related problems (DRPs) among elderly patients from surgical departments. The current study is aimed at identifying and categorizing types of DRPs and assessing the severities of the DRPs. Medication orders for hospitalized patients aged ≥65 years from six surgery departments were reviewed to determine DRPs over 6 months in a tertiary teaching hospital of Chongqing, China. DRPs were classified based on the Pharmaceutical Care Network Europe classification V8.02. The severity ratings of the DRPs were assessed using the National Coordinating Council for Medication Error Reporting and Prevention classification. A total of 53,231 medication orders from 1,707 elderly patients were reviewed, and 1,061 DRPs were identified. Treatment safety (44.9%) was the most common DRP type. Drug selection (43.1%) and dose selection (43.1%) were the major causes of DRPs. A total of 75.1% of the DRPs were classified into severity categories B to D (causing no or potential harm), and 24.9% were classified as categories E to H (causing actual harm). DRPs are common in hospitalized elderly surgical patients. Pharmacists should provide medication order reviews in this vulnerable patient population.
外科老年患者的药物相关问题（DRPs）数据缺乏。本研究旨在确定和分类 DRPs 的类型，并评估 DRPs 的严重程度。对中国重庆一家三级教学医院六个外科科室≥65 岁住院患者的医嘱进行回顾性分析，以确定 6 个月内的 DRPs。根据欧洲药学保健网络分类 V8.02 对 DRPs 进行分类。使用国家协调用药错误报告和预防分类对 DRPs 的严重程度进行评估。共回顾了 1707 名老年患者的 53231 份用药医嘱，发现了 1061 例 DRPs。治疗安全性（44.9%）是最常见的 DRP 类型。药物选择（43.1%）和剂量选择（43.1%）是 DRPs 的主要原因。75.1%的 DRPs 被分类为 B 至 D 类（无或潜在危害），24.9%被分类为 E 至 H 类（实际危害）。DRPs 在住院老年外科患者中很常见。药师应在这一脆弱患者群体中提供用药医嘱审核。
