College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China.
Department of Medical Imaging, the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.
J Sports Sci. 2021 Jul;39(14):1621-1632. doi: 10.1080/02640414.2021.1891722. Epub 2021 Feb 25.
The current study examined the effects of an 11-week exercise intervention on brain activity during a working memory (WM) task and resting-state functional network connectivity in deaf children. Twenty-six deaf children were randomly assigned to either an 11-week exercise intervention or control conditions. Before and after the exercise intervention, all participants were scanned with functional magnetic resonance imaging (fMRI) during N-back task performance and a resting state. The behavioural results showed that the exercise intervention improved WM performance. Task activation analyses showed an increase in the parietal, occipital, and temporal gyri and hippocampus and hippocampus (HIP). In addition, WM performance improvements were associated with greater activation in the left HIP region. Resting-state functional connectivity (Rs-FC) between HIP and certain other brain areas shown a significant interaction of group (exercise versus no exercise) and time (pre- and postintervention). Moreover, connectivity between the left HIP and left middle frontal gyrus was related to improved WM performance. These data extend current knowledge by indicating that an exercise intervention can improve WM in deaf children, and these enhancements may be related to the WM network plasticity changes induced by exercise.
本研究旨在探讨 11 周运动干预对聋童工作记忆（WM）任务期间大脑活动和静息态功能网络连通性的影响。26 名聋童被随机分配到运动干预组或对照组。在运动干预前后，所有参与者都接受了功能磁共振成像（fMRI）扫描，扫描内容包括 N-back 任务表现和静息状态。行为学结果表明，运动干预提高了 WM 表现。任务激活分析显示顶叶、枕叶和颞叶以及海马体（HIP）的活跃度增加。此外，WM 表现的提高与 HIP 左区的更大活跃度相关。静息态功能连接（Rs-FC）在 HIP 和其他一些大脑区域之间显示出组（运动干预与非运动干预）和时间（干预前后）的显著交互作用。此外，左侧 HIP 与左侧额中回之间的连接与 WM 表现的提高有关。这些数据通过表明运动干预可以提高聋童的 WM，扩展了当前的知识，并且这些增强可能与运动引起的 WM 网络可塑性变化有关。
