van den Bosch R J, Rozendaal N, Mol J M
University of Groningen, The Netherlands.
Psychiatry Res. 1988 Feb;23(2):201-8. doi: 10.1016/0165-1781(88)90010-8.
The contingent negative variation (CNV) was used to study cortical activation in frontal and central areas in psychotic and nonpsychotic patients. Psychotic patients showed a higher frontal relative to central CNV amplitude than nonpsychotic patients, a finding that was correlated with performance on a test of frontal function. Negative symptom ratings (physical anhedonia and social closeness) were correlated with relatively low frontal versus central CNV amplitude, but only in psychotic patients.
利用关联性负变（CNV）来研究精神病患者和非精神病患者额叶及中央区域的皮质激活情况。与非精神病患者相比，精神病患者额叶相对于中央的CNV波幅更高，这一发现与额叶功能测试表现相关。阴性症状评分（躯体快感缺失和社交亲密度）与额叶相对于中央较低的CNV波幅相关，但仅见于精神病患者。
