van den Bosch R J, Rozendaal N
Department of Psychiatry, University of Groningen, The Netherlands.
Biol Psychiatry. 1988 Nov;24(7):741-6. doi: 10.1016/0006-3223(88)90249-1.
The relationships between subjective cognitive dysfunction (so-called basic symptoms) and some psychophysiological measures were examined repeatedly in schizophrenic and schizoaffective patients during an acute psychotic episode, and comparisons were made with psychotic symptom ratings. Psychophysiological variables were: quality of eye tracking, amplitude measures of the contingent negative variation, and reaction time. Ratings of psychotic and basic symptoms were significantly correlated, but only the basic symptom score showed significant associations with eye tracking, contingent negative variation, and reaction time. Although this pattern was confined to the recovery phase of the psychotic episode, the results suggest that the core psychopathological correlates of these psychophysiological measures consist of basic symptoms rather than florid psychotic symptoms.
在精神分裂症和分裂情感性障碍患者的急性精神病发作期间，反复检查了主观认知功能障碍（所谓的基本症状）与一些心理生理指标之间的关系，并与精神病症状评分进行了比较。心理生理变量包括：眼动追踪质量、关联性负变的幅度测量以及反应时间。精神病症状和基本症状评分显著相关，但只有基本症状评分与眼动追踪、关联性负变和反应时间显示出显著关联。尽管这种模式仅限于精神病发作的恢复期，但结果表明，这些心理生理指标的核心精神病理学关联因素是基本症状而非明显的精神病症状。
