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[妊娠期心肌病。β-拟交感神经药的潜在作用]

[Myocardiopathies during pregnancy. Possible role of beta-mimetics].

作者信息

Daubert J C, Gosse P, Rio M, Grall J Y, Bourdonnec C, Pony J C, Gouffault J

出版信息

Arch Mal Coeur Vaiss. 1978 Nov;71(11):1283-90.

PMID:33631
Abstract

The authors report two cases of severe non-obstructive cardiomyopathy presenting at the end of pregnancy in young women treated for long periods and at high dosage with beta 2-adrenoceptor stimulants, prescribed for threatened abortion or premature labour. The circumstances of the presentation, the clinical prescribed for threatened abortion or premature labour. The circumstances of the presentation, the clinical picture and the course towards complete recovery suggest that this might be a pathological process different from "cardiomyopathy of pregnancy" and be an "adrenergic myocarditis" induced or made worse by these drugs. The authors deduce some simple preventive measures.

摘要

作者报告了两例严重非梗阻性心肌病的病例,发生在年轻女性妊娠末期,她们因先兆流产或早产而长期大剂量使用β2肾上腺素能受体兴奋剂进行治疗。发病情况、临床表现以及完全康复的过程表明,这可能是一种不同于“妊娠心肌病”的病理过程,而是由这些药物诱发或加重的“肾上腺素能心肌炎”。作者推断出一些简单的预防措施。

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