Mulowooza Jude, Santos Nicole, Isabirye Nathan, Inhensiko Innocent, Sloan Nancy L, Shah Sachita, Butrick Elizabeth, Waiswa Peter, Walker Dilys
Makerere University, School of Public Health, P.O Box 7072, Kampala, Uganda.
Institute for Global Health Sciences, University of California San Francisco, 550 16th Street, 3rd floor, San Francisco, CA 94158 United States.
Midwifery. 2021 May;96:102949. doi: 10.1016/j.midw.2021.102949. Epub 2021 Feb 12.
The aim of this study was to evaluate the effect of a midwife-performed checklist and limited obstetric ultrasound on sensitivity and positive predictive value for a composite outcome comprising multiple gestation, placenta praevia, oligohydramnios, preterm birth, malpresentation, abnormal foetal heart rate.
Quasi-experimental pre-post intervention study.
Maternity unit at a district hospital in Eastern Uganda.
Interventions were implemented in a phased approach: standardised labour triage documentation (Phase 1), a triage checklist (Phase 2), and checklist plus limited obstetric ultrasound (Phase 3).
Consenting women presenting to labour triage for admission after 28 weeks of gestation between February 2018 and June 2019 were eligible. Women not in labour or those requiring immediate care were excluded. 3,865 women and 3,937 newborns with similar sample sizes per phase were included in the analysis.
Outcome data after birth were used to determine true presence of a complication, while intake and checklist data were used to inform diagnosis before birth. Compared to Phase 1, Phase 2 and 3 interventions improved sensitivity (Phase 1: 47%, Phase 2: 68.8%, Phase 3: 73.5%; p ≤ 0.001) and reduced positive predictive value (65.9%, 55%, 48.7%, p ≤ 0.001) for the composite outcome. No phase differences in adverse maternal or foetal outcomes were observed.
Both a triage checklist and a checklist plus limited obstetric ultrasound improved accurate identification of cases with some increase in false positive diagnosis. These interventions may be beneficial in a resource-limited maternity triage setting to improve midwives' diagnoses and clinical decision-making.
本研究旨在评估由助产士执行的检查表和有限的产科超声检查对包括多胎妊娠、前置胎盘、羊水过少、早产、胎位异常、胎儿心率异常在内的综合结局的敏感性和阳性预测值的影响。
干预前后的准实验研究。
乌干达东部一家地区医院的产科病房。
干预措施分阶段实施:标准化分娩分诊记录(第1阶段)、分诊检查表(第2阶段)以及检查表加有限的产科超声检查(第3阶段)。
2018年2月至2019年6月期间,妊娠28周后到分娩分诊处要求入院的同意参与的妇女符合条件。未临产的妇女或需要立即治疗的妇女被排除。分析纳入了3865名妇女和3937名新生儿,每个阶段的样本量相似。
出生后的结局数据用于确定并发症的实际存在情况,而入院时的数据和检查表数据则用于在出生前进行诊断。与第1阶段相比,第2阶段和第3阶段的干预措施提高了综合结局的敏感性(第1阶段:47%,第2阶段:68.8%,第3阶段:73.5%;p≤0.001),并降低了阳性预测值(65.9%、55%、48.7%,p≤0.001)。未观察到母婴不良结局的阶段差异。
分诊检查表以及检查表加有限的产科超声检查都提高了病例识别的准确性,但假阳性诊断略有增加。这些干预措施可能有利于资源有限的产科分诊环境,以改善助产士的诊断和临床决策。