Department of Physical Therapy, Faculty of Health and Welfare, Tokushima Bunri University, Tokushima City, Japan.
Department of Physical Therapy, Faculty of Health and Welfare, Tokushima Bunri University, Tokushima City, Japan.
Nutrition. 2021 Jun;86:111175. doi: 10.1016/j.nut.2021.111175. Epub 2021 Jan 29.
As the extracellular-to-intracellular water (ECW/ICW) ratio of the thigh is negatively associated with knee extension strength or gait speed in the elderly, an increase in the total body ECW/ICW ratio in the elderly is considered to be related to a decrease in physical function. However, these relationships have not been properly investigated. The aim of this study was to investigate the relationship of handgrip strength and gait speed with the total body ECW/ICW ratio in community-dwelling elderly women.
The present study used a cross-sectional design. We enrolled 71 community-dwelling women, ≥65 y of age, who could independently perform activities of daily living. The total body ECW/ICW ratio was measured using bioelectrical impedance analysis. Relationships between the total body ECW/ICW ratio and grip strength and gait speed were assessed using Pearson's correlation coefficient. Additionally, stepwise multiple regression analysis was used to identify the factors that were independently associated with handgrip strength and gait speed. The independent variables considered were the total body ECW/ICW ratio, age, body mass index, number of medications, presence of pain, and a history of certain conditions.
The results indicated that an increased total body ECW/ICW ratio in community-dwelling elderly women was associated with a decreased handgrip strength and gait speed. Furthermore, the total body ECW/ICW ratio was significantly, independently associated with handgrip strength even after adjusting for confounding factors.
These findings suggest that the total body ECW/ICW ratio may indicate health conditions in community-dwelling elderly women.
大腿的细胞外液/细胞内液（ECW/ICW）比值与老年人的膝关节伸展力量或步速呈负相关，因此老年人的全身 ECW/ICW 比值增加被认为与身体功能下降有关。然而，这些关系尚未得到妥善研究。本研究旨在探讨社区居住的老年女性的手握力和步速与全身 ECW/ICW 比值的关系。
本研究采用横断面设计。我们招募了 71 名≥65 岁、能够独立进行日常生活活动的社区居住女性。使用生物电阻抗分析测量全身 ECW/ICW 比值。使用 Pearson 相关系数评估全身 ECW/ICW 比值与握力和步速之间的关系。此外，使用逐步多元回归分析确定与手握力和步速独立相关的因素。考虑的自变量包括全身 ECW/ICW 比值、年龄、体重指数、用药数量、疼痛存在情况以及某些疾病的病史。
结果表明，社区居住的老年女性全身 ECW/ICW 比值增加与手握力和步速下降有关。此外，即使在调整混杂因素后，全身 ECW/ICW 比值与手握力仍具有显著的独立相关性。
这些发现表明，全身 ECW/ICW 比值可能反映了社区居住的老年女性的健康状况。
