特发性肺纤维化合并 2 型糖尿病的发病率及预测因素：弗里曼特尔糖尿病研究 I 期。
Incidence and predictors of idiopathic pulmonary fibrosis complicating Type 2 diabetes: the Fremantle Diabetes Study Phase I.
机构信息
Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.
Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
出版信息
Intern Med J. 2021 Feb;51(2):276-279. doi: 10.1111/imj.15191.
During 106 865 person-years of follow up, 17 (1.3%) Fremantle Diabetes Study Phase I participants with Type 2 diabetes and 57 (1.1%) matched individuals without diabetes developed idiopathic pulmonary fibrosis (IPF), an incidence rate ratio (95% confidence interval) of 1.40 (0.76-2.44) (P = 0.22). In the diabetes cohort, age at diabetes diagnosis and total serum cholesterol (inversely) predicted incident IPF in competing risk multivariable models. The incidence of IPF was low in community-based cohorts, regardless of Type 2 diabetes status.
在 106865 人年的随访中，17 名（1.3%）2 型糖尿病的弗里曼特尔糖尿病研究 I 期参与者和 57 名（1.1%）匹配的无糖尿病个体发生了特发性肺纤维化（IPF），发病率比（95%置信区间）为 1.40（0.76-2.44）（P=0.22）。在糖尿病队列中，糖尿病诊断时的年龄和总血清胆固醇（呈负相关）在竞争风险多变量模型中预测了 IPF 的发病。无论 2 型糖尿病状态如何，基于社区的队列中 IPF 的发病率都很低。
Zotero 插件