Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, China.
China National Accreditation Insititute for Conformity Assessment, No. 8 Nanhuashi Dajie Chongwen District, Beijing 10086, China.
Mar Genomics. 2021 Apr;56:100818. doi: 10.1016/j.margen.2020.100818. Epub 2020 Sep 15.
Microbacterium sediminis YLB-01, a piezotolerant and psychrotolerant actinomycete, was isolated from deep-sea sediment of the South-West Indian Ocean and could be a good model for understanding the adaptation of extremophiles to the benthic piezosphere. Here, we report the analysis of the complete genome sequence of strain YLB-01. The genome sequence consists of a single circular chromosome comprising 2,792,195 bp and a linear plasmid comprising 127,669 bp with G + C content of 71.76 and 68.49 mol%, respectively. In this regard, strain YLB-01 possesses the smallest genome size but the highest G + C content among the genus Microbacterium sequenced to date. As the first complete genome sequence of the genus Microbacterium isolated from deep-sea environment, the strain YLB-01 genome is unique or enriched in genes involved in xenobiotics biodegradation and metabolism, compatible solutes, and transposases, some of which might be related to bacterial enhancement of ecological fitness in the deep sea.
深海沉积物中分离到一株耐高压和耐低温放线菌微小杆菌 YLB-01，它可能是研究极端微生物适应深海海底高压环境的良好模型。本文报道了该菌株的全基因组序列分析结果。基因组由一条大小为 2792195bp 的环状染色体和一条大小为 127669bp 的线性质粒组成，G+C 含量分别为 71.76%和 68.49%。在已测序的微小杆菌属菌株中，YLB-01 具有最小的基因组大小但最高的 G+C 含量。作为首例从深海环境中分离到的微小杆菌属全基因组序列，YLB-01 基因组在参与生物降解和代谢、相容性溶质和转座酶的基因上具有独特性或丰富性，其中一些基因可能与细菌在深海中增强生态适应性有关。
