Gong Qing-Long, Wang Qi, Yang Xue-Yao, Li Dong-Li, Zhao Bo, Ge Gui-Yang, Zong Ying, Li Jian-Ming, Leng Xue, Shi Kun, Liu Fei, Du Rui
College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
College of Chinese Medicine Materials, Jilin Agricultural University, Changchun, China.
Front Vet Sci. 2021 Jan 28;7:550381. doi: 10.3389/fvets.2020.550381. eCollection 2020.
Bluetongue caused by the bluetongue virus (BTV) is a non-contagious and an insect-borne disease mainly affecting domestic and wild ruminants. Bluetongue in cattle is associated with vesicular lesions, weight loss, low milk production, and low reproductive capacity. It should not be ignored as it is associated with large economic losses to the livestock breeding industry in China. Although many studies have investigated bluetongue virus infection in cattle, no nationwide study on the prevalence of bluetongue virus infection in cattle from China has yet been conducted. This meta-analysis aimed to evaluate the seroprevalence and risk factors for bluetongue in cattle. We collected 50 publications from 1988 to 2019 through PubMed, ScienceDirect, Chinese Web of Knowledge (CNKI), VIP Chinese journal database, and Wanfang database. A total of the pooled bluetongue seroprevalence of 12.2% (5,332/87,472) in cattle was tested. The point estimate of bluetongue collected from 2001 to 2011 was 22.5% (95% CI: 1.2-58.9), which was higher than after 2012 (9.9%, 95% CI: 3.3-19.4). The analysis of the feeding model subgroup revealed that the seroprevalence of bluetongue was significantly higher ( < 0.05) among free-range cattle (22.5%; 95% CI: 7.7-42.3) than among cattle from intensive farming systems (1.8%; 95% CI: 0.0-6.7). The seroprevalence of bluetongue in different species showed significant variation ( < 0.05), with the highest seroprevalence of 39.8% (95% CI: 18.7-63.0) in buffalo and the lowest seroprevalence of 4.3% (95% CI: 1.2-9.0) in yak. In the zoogeographical division subgroup, the seroprevalence of bluetongue correlated positively within a certain range with the species distribution of . Our findings suggested that bluetongue was prevalent in cattle in China. In addition, the contact with sheep, other ruminants, or transmission media such as may increase the seroprevalence of bluetongue disease in cattle. It is necessary to carry out continuous monitoring of the bluetongue seroprevalence. Moreover, comprehensive and improved strategies and measures should be implemented to prevent and control the spread of bluetongue.
由蓝舌病病毒（BTV）引起的蓝舌病是一种非传染性的昆虫传播疾病，主要影响家养和野生反刍动物。牛的蓝舌病与水疱性病变、体重减轻、产奶量低和繁殖能力低有关。由于它给中国畜牧业带来巨大经济损失，因此不容忽视。尽管许多研究调查了牛的蓝舌病病毒感染情况，但尚未有关于中国牛群中蓝舌病病毒感染率的全国性研究。这项荟萃分析旨在评估牛蓝舌病的血清阳性率和危险因素。我们通过PubMed、ScienceDirect、中国知网（CNKI）、维普中文期刊数据库和万方数据库收集了1988年至2019年的50篇出版物。共检测了牛群中蓝舌病血清阳性率的合并值为12.2%（5332/87472）。2001年至2011年收集的蓝舌病点估计值为22.5%（95%可信区间：1.2 - 58.9），高于2012年之后（9.9%，95%可信区间：3.3 - 19.4）。饲养模式亚组分析显示，自由放养牛群中蓝舌病的血清阳性率（22.5%；95%可信区间：7.7 - 42.3）显著高于集约化养殖系统中的牛群（1.8%；95%可信区间：0.0 - 6.7）（P < 0.05）。不同物种中蓝舌病的血清阳性率显示出显著差异（P < 0.05）水牛的血清阳性率最高，为39.8%（95%可信区间：18.7 - 63.0），牦牛的血清阳性率最低，为4.3%（95%可信区间：1.2 - 9.0）。在动物地理分区亚组中，蓝舌病的血清阳性率在一定范围内与[具体内容缺失]的物种分布呈正相关。我们的研究结果表明蓝舌病在中国牛群中普遍存在。此外，与绵羊、其他反刍动物或[具体传播媒介缺失]等传播媒介的接触可能会增加牛群中蓝舌病的血清阳性率。有必要对蓝舌病血清阳性率进行持续监测。此外，应实施全面且改进的策略和措施来预防和控制蓝舌病的传播。
