Bakhtiarydavijani A, Khalid G, Murphy M A, Johnson K L, Peterson L E, Jones M, Horstemeyer M F, Dobbins A C, Prabhu R K
Center for Advanced Vehicular Systems, Mississippi State University, Starkville, MS, USA.
Middle Technical University, Baghdad, Iraq.
Comput Methods Biomech Biomed Engin. 2021 Aug;24(11):1169-1183. doi: 10.1080/10255842.2020.1867851. Epub 2021 Feb 26.
Chronic Traumatic Encephalopathy (CTE) affects a significant portion of athletes in contact sports but is difficult to quantify using clinical examinations and modeling approaches. We use an approach to quantify CTE biomechanics using mesoscale Finite Element (FE) analysis that bridges with macroscale whole head FE analysis. The sulci geometry produces complex stress waves that interact with one another to create increased shear stresses at the sulci depth that are significantly larger than in analyses without sulci (from 0.5 to 18.0 kPa). Sulci peak stress concentration regions coincide with experimentally observed CTE sites documented in the literature. HighlightsSulci introduce stress localizations at their depth in the gray matterSulci stress fields interact to produce stress concentration sites in white matterDifferentiating brain tissue properties did not significantly affect peak stresses.
慢性创伤性脑病（CTE）影响着相当一部分从事接触性运动的运动员，但使用临床检查和建模方法很难对其进行量化。我们采用一种方法，通过中尺度有限元（FE）分析来量化CTE生物力学，并与宏观尺度的全脑FE分析相衔接。脑沟几何形状会产生复杂的应力波，这些应力波相互作用，在脑沟深度处产生增加的剪应力，其显著大于没有脑沟的分析结果（从0.5到18.0kPa）。脑沟峰值应力集中区域与文献中记录的实验观察到的CTE部位一致。要点脑沟在灰质深度处引入应力局部化脑沟应力场相互作用，在白质中产生应力集中部位区分脑组织特性对峰值应力没有显著影响。
