Meier J, Adler C, Stocker K
Pentapharm Ltd, Basle, Switzerland.
Toxicon. 1988;26(2):218-21. doi: 10.1016/0041-0101(88)90175-4.
The isoelectric point of Protac was recently estimated to be at pH 3. However, further investigations using different experimental procedures revealed that Protac, due to its particular binding properties, is able to form complexes with carrier ampholytes. Thus, the actual isoelectric point of Protac was found to be in the basic region.
最近估计Protac的等电点在pH 3。然而,使用不同实验程序的进一步研究表明,由于其特殊的结合特性,Protac能够与载体两性电解质形成复合物。因此,发现Protac的实际等电点处于碱性区域。