Department of Nephrology, Kaiser Permanente, Fontana, CA.
Perm J. 2020 Dec;25:1. doi: 10.7812/TPP/20.140.
The present pandemic of severe acute respiratory syndrome is caused by the coronavirus (2019-nCoV), commonly called COVID-19. Starting from China, it has spread worldwide, causing major morbidity and mortality. It primarily involves the pulmonary system, but other organ systems are not spared. Treatment is still elusive and evolving. The exact pathogenesis of renal damage from COVID-19 virus and the magnitude of renal failure in this infection are not very clear. PubMed was searched to identify published literature from 2019 to present using the following keywords: COVID-19, acute kidney injury, creatinine, blood urea nitrogen, chronic kidney disease, renal replacement therapy, and dialysis. Cited references were also used to further identify relevant articles and literature elsewhere on the web. This review looks at the burden and influence of the COVID-19 pandemic on the kidneys and on the implications it will have on public health planning.
目前严重急性呼吸系统综合症的大流行是由冠状病毒(2019-nCoV)引起的,通常称为 COVID-19。它始于中国,已在全球范围内传播,造成了重大的发病率和死亡率。它主要涉及肺部系统,但其他器官系统也不能幸免。治疗仍然难以捉摸,并且还在不断发展。COVID-19 病毒引起的肾脏损害的确切发病机制以及这种感染引起的肾衰竭的程度尚不清楚。使用以下关键字在 PubMed 上搜索以确定 2019 年至今发表的文献:COVID-19、急性肾损伤、肌酐、血尿素氮、慢性肾脏病、肾脏替代治疗和透析。还使用引用的参考文献在网络上的其他地方进一步确定相关文章和文献。本综述探讨了 COVID-19 大流行对肾脏的影响及其对公共卫生规划的影响。