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COVID-19 大流行与急性肾损伤负担:已知与未知。

COVID-19 Pandemic and the Burden of Acute Kidney Injury: The Known and the Unknown.

机构信息

Department of Nephrology, Kaiser Permanente, Fontana, CA.

出版信息

Perm J. 2020 Dec;25:1. doi: 10.7812/TPP/20.140.

DOI:10.7812/TPP/20.140
PMID:33635771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8817931/
Abstract

The present pandemic of severe acute respiratory syndrome is caused by the coronavirus (2019-nCoV), commonly called COVID-19. Starting from China, it has spread worldwide, causing major morbidity and mortality. It primarily involves the pulmonary system, but other organ systems are not spared. Treatment is still elusive and evolving. The exact pathogenesis of renal damage from COVID-19 virus and the magnitude of renal failure in this infection are not very clear. PubMed was searched to identify published literature from 2019 to present using the following keywords: COVID-19, acute kidney injury, creatinine, blood urea nitrogen, chronic kidney disease, renal replacement therapy, and dialysis. Cited references were also used to further identify relevant articles and literature elsewhere on the web. This review looks at the burden and influence of the COVID-19 pandemic on the kidneys and on the implications it will have on public health planning.

摘要

目前严重急性呼吸系统综合症的大流行是由冠状病毒(2019-nCoV)引起的,通常称为 COVID-19。它始于中国,已在全球范围内传播,造成了重大的发病率和死亡率。它主要涉及肺部系统,但其他器官系统也不能幸免。治疗仍然难以捉摸,并且还在不断发展。COVID-19 病毒引起的肾脏损害的确切发病机制以及这种感染引起的肾衰竭的程度尚不清楚。使用以下关键字在 PubMed 上搜索以确定 2019 年至今发表的文献:COVID-19、急性肾损伤、肌酐、血尿素氮、慢性肾脏病、肾脏替代治疗和透析。还使用引用的参考文献在网络上的其他地方进一步确定相关文章和文献。本综述探讨了 COVID-19 大流行对肾脏的影响及其对公共卫生规划的影响。

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本文引用的文献

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Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection.人类肾脏是新型严重急性呼吸综合征冠状病毒 2 感染的靶器官。
Nat Commun. 2021 May 4;12(1):2506. doi: 10.1038/s41467-021-22781-1.
2
Collapsing glomerulopathy in a COVID-19 patient.一名新冠肺炎患者的塌陷性肾小球病
Kidney Int. 2020 Jul;98(1):228-231. doi: 10.1016/j.kint.2020.04.006. Epub 2020 Apr 15.
3
Angiotensin-Converting Enzyme 2 and Antihypertensives (Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors) in Coronavirus Disease 2019.血管紧张素转换酶 2 与抗高血压药物(血管紧张素受体阻滞剂和血管紧张素转换酶抑制剂)在 2019 冠状病毒病中的作用。
Mayo Clin Proc. 2020 Jun;95(6):1222-1230. doi: 10.1016/j.mayocp.2020.03.026. Epub 2020 Apr 4.
4
Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China.中国 26 例 COVID-19 死亡患者的肾脏组织病理分析。
Kidney Int. 2020 Jul;98(1):219-227. doi: 10.1016/j.kint.2020.04.003. Epub 2020 Apr 9.
5
Collapsing Glomerulopathy in a Patient With COVID-19.一名新冠肺炎患者的塌陷性肾小球病
Kidney Int Rep. 2020 Apr 9;5(6):935-939. doi: 10.1016/j.ekir.2020.04.002. eCollection 2020 Jun.
6
Drug Evaluation during the Covid-19 Pandemic.新冠疫情期间的药物评估
N Engl J Med. 2020 Jun 11;382(24):2282-2284. doi: 10.1056/NEJMp2009457. Epub 2020 Apr 14.
7
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review.药物治疗 2019 冠状病毒病(COVID-19):综述。
JAMA. 2020 May 12;323(18):1824-1836. doi: 10.1001/jama.2020.6019.
8
COVID-19 and Kidney Failure in the Acute Care Setting: Our Experience From Seattle.急性护理环境中的新冠肺炎与肾衰竭:我们在西雅图的经验
Am J Kidney Dis. 2020 Jul;76(1):4-6. doi: 10.1053/j.ajkd.2020.04.001. Epub 2020 Apr 8.
9
The COVID-19 Pandemic in the US: A Clinical Update.美国的新冠疫情:临床最新情况
JAMA. 2020 May 12;323(18):1767-1768. doi: 10.1001/jama.2020.5788.
10
Kidney disease is associated with in-hospital death of patients with COVID-19.肾病与 COVID-19 患者住院期间的死亡相关。
Kidney Int. 2020 May;97(5):829-838. doi: 10.1016/j.kint.2020.03.005. Epub 2020 Mar 20.