Laboratory of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Graduate School of Fisheries and Environmental Sciences, Nagasaki University, Bunkyo, Nagasaki, Nagasaki 852-8521, Japan.
J Wildl Dis. 2021 Jan 6;57(1):205-210. doi: 10.7589/JWD-D-20-00041.
We describe a case of systemic toxoplasmosis in a female adult narrow-ridged finless porpoise (Neophocaena asiaeorientalis) found in May 2018 inside a gillnet set in the Ariake Sound, southern Japan. The main lesions observed were lymphoplasmacytic and focally necrotizing encephalitis, necrotizing to granulomatous adrenalitis, myocarditis, and inflammation in the intestinal wall, associated with protozoal tissue cysts and tachyzoites. Additionally, the individual had a 5.6 mm (crown-rump length) early-stage embryo in the left uterine horn, which had multifocal necrotizing lesions with intralesional tissue cysts and tachyzoites in the parenchyma. Immunohistochemistry and PCR and sequencing of the internal transcribed spacer 1 region confirmed a Toxoplasma gondii infection. Further genotyping revealed an atypical type II genotype with a type I pattern for the Apico locus. Narrow-ridged finless porpoises are an endangered coastal species already facing various anthropogenic threats. Toxoplasmosis, especially with its ability to transmit to an early-stage embryo, should be considered an emerging threat to this vulnerable species.
我们描述了一起发生在 2018 年 5 月日本南部有明海刺网中的一例成年雌性窄颅江豚（Neophocaena asiaeorientalis）的全身弓形虫病病例。观察到的主要病变是淋巴浆细胞性和局灶性坏死性脑炎、坏死性至肉芽肿性肾上腺炎、心肌炎和肠壁炎症，伴有原虫组织囊肿和速殖子。此外，该个体的左侧子宫角中有一个 5.6 毫米（头臀长）的早期胚胎，其实质内有多个局灶性坏死病变，伴有组织囊肿和速殖子。免疫组织化学和 PCR 以及内部转录间隔区 1 区域的测序证实了弓形虫感染。进一步的基因分型显示出一种非典型的 II 型基因型，其 Apico 基因座呈 I 型模式。窄颅江豚是一种濒危的沿海物种，已经面临着各种人为威胁。弓形虫病，特别是其能够传播到早期胚胎的能力，应该被视为对这一脆弱物种的新出现威胁。
