Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
BMC Surg. 2021 Feb 26;21(1):104. doi: 10.1186/s12893-021-01097-3.
Breast augmentation with polyacrylamide gel (PAAG) injection was approved in China in 1998 and later banned in 2006. The ban ensued numerous complaints from patients such as pain, induration, deformation, infection, displacement, and milk deposition associated with PAAG injection. To date, no study has investigated the long-term effect of PAAG migration on autoimmune diseases.
We report a rare case of a 49-year-old female patient with familial vitiligo who receiving PAAG injection for breast augmentation. The patient reported to have felt persistent movement of PAAG in her thoracoabdominal area for almost 20 years. Furthermore, the PAAG-induced chronic inflammation that aggravated vitiligo, which in turn promoted skin sclerosis. This damaged the breast contracture, increased chest tightness and induced mild breathing problems.
Here, we present a rare case in which a patient with a family history of vitiligo experienced long-term complications after receiving PAAG injection for breast augmentation. This case highlights the relationship between vitiligo, migration of PAAG and tissue hardening and skin contraction.
Level V.
聚丙烯酰胺水凝胶（PAAG）注射隆乳术于 1998 年在中国获得批准，后于 2006 年被禁止。禁令出台后，众多患者出现了与 PAAG 注射相关的诸多并发症，如疼痛、硬结、变形、感染、移位和积乳等。迄今为止，尚无研究调查 PAAG 迁移对自身免疫性疾病的长期影响。
我们报告了一例罕见的 49 岁女性家族性白癜风患者接受 PAAG 注射隆乳的病例。该患者自述近 20 年来一直感到胸腹部有 PAAG 的持续移动。此外，PAAG 引起的慢性炎症加重了白癜风，进而导致皮肤硬化。这破坏了乳房的收缩，增加了胸部紧绷感，并引起了轻度呼吸问题。
本案例报告了一例有家族性白癜风病史的患者在接受 PAAG 注射隆乳后出现长期并发症的罕见情况。该病例强调了白癜风、PAAG 迁移与组织硬化和皮肤收缩之间的关系。
5 级。
