Schön Klinik München Harlaching, Spine Center, Harlachinger Str. 51, 81547, Munich, Germany.
Academic Teaching Hospital and Spine Research Institute, Paracelsus Medical University, Salzburg, Austria.
Eur Spine J. 2021 Apr;30(4):936-945. doi: 10.1007/s00586-021-06765-9. Epub 2021 Feb 27.
Decompression is one of the most common interventions in spinal surgery. Obesity has become an increasing issue in surgical patients. Therefore, the aim of this study was to analyze the clinical outcome following lumbar microsurgical decompression in correlation with the patient's body mass index (BMI).
A toal of 744 patients with spinal claudication that were seen at two specialized spine centers were included in this study. All patients underwent a bilateral microsurgical decompression in over-the-top technique. Patients were allocated in 4 groups based in their BMI category: 18.5-24.9 (n = 204), 25.0-29.9 (n = 318), 30.0-34.9 (n = 164) and ≥ 35 (n = 58). Clinical outcome data were recorded at baseline as well as 3, 12 and 24 months thereafter within a prospective study framework. The minimum follow-up was 12 months. For statistical analysis, data were adjusted for age, length of surgery and ASA and were analyzed by generalized linear gamma-based models.
Postoperative changes in all outcome parameters were clearly dependent on BMI. Patients with higher BMI were characterized by inferior baseline values for VAS Back (p < 0.05). Over the follow-up period, the groups with BMI 30-34.9 and BMI ≥ 35 benefitted significantly less from the surgery than the two slimmer groups (p < 0.05).
The data obtained from this large, homogenous cohort demonstrate that the quality of life improved substantially in all patients that were treated microsurgically for spinal stenosis. However, a BMI ≥ 30 may be considered as a negative predictor for a significantly inferior clinical outcome.
减压是脊柱手术中最常见的干预措施之一。肥胖已成为手术患者日益关注的问题。因此,本研究旨在分析腰椎微创手术减压与患者体重指数(BMI)之间的临床疗效相关性。
本研究共纳入了在两个专业脊柱中心就诊的 744 例脊柱狭窄患者。所有患者均接受双侧过顶式显微减压术。根据 BMI 类别将患者分为 4 组:18.5-24.9(n=204)、25.0-29.9(n=318)、30.0-34.9(n=164)和≥35(n=58)。在前瞻性研究框架内,记录基线及术后 3、12 和 24 个月的临床疗效数据。最低随访时间为 12 个月。为了进行统计学分析,对年龄、手术时间、ASA 等因素进行了调整,并采用广义线性伽马模型进行分析。
所有疗效参数的术后变化明显与 BMI 相关。BMI 较高的患者,VAS 腰痛基线值较低(p<0.05)。在随访期间,BMI 在 30-34.9 及 BMI≥35 的组与较瘦的两组相比,手术获益明显较小(p<0.05)。
本大规模、同质队列研究的数据表明,所有接受脊柱狭窄显微手术治疗的患者生活质量均有显著改善。然而,BMI≥30 可能被视为临床疗效显著降低的负性预测因素。