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腰椎管狭窄症:单侧入路双侧显微减压的预后因素。

Lumbar spinal stenosis: prognostic factors for bilateral microsurgical decompression using a unilateral approach.

机构信息

Center for Spine Surgery, Eilbek Medical Center, Hamburg, Germany. lpapavero@ schoen- kliniken.de

出版信息

Neurosurgery. 2009 Dec;65(6 Suppl):182-7; discussion187. doi: 10.1227/01.NEU.0000341906.65696.08.

Abstract

OBJECTIVE

We describe a prospective cohort study that investigated the effectiveness of microsurgical bilateral decompression using unilateral laminotomy for lumbar spinal stenosis and assessed the factors influencing the outcome.

METHODS

A total of 165 consecutive patients underwent decompression for lumbar spinal stenosis. They were divided into 3 age groups: A (<65 years), B (65-75 years), and C (>75 years). Further classification was performed according to body mass index (BMI): BMI 1 (<26), BMI 2 (26-30), and BMI 3 (>30), anesthesiological risk factors (American Society of Anesthesiologists), and the number of levels decompressed. The outcome was monitored by an independent observer at 1 week, 3 months, and 1 year after surgery. The following parameters were evaluated: pain (visual analog scale and analgesic consumption), functional improvement (Neurogenic Claudication Outcome Score), and walking performance, defined as walking distance x speed (treadmill).

RESULTS

One week after surgery, pain decreased in 85.9% of patients, and a comparison of the pre- and postoperative use of analgesics showed that 38% of nonopioid use and 74% of opioid use were discontinued, whereas nonsteroidal anti-inflammatory drug consumption increased 13%. One year after surgery, pain remained decreased in 83.9% of patients, Neurogenic Claudication Outcome Score increased in 90.3% of patients, and walking performance improved in 92.2% of patients. BMI greater than 30 was the only negative prognostic factor for pain reduction (P = 0.012) and Neurogenic Claudication Outcome Score improvement (P = 0.019). Surprisingly, patients who underwent multilevel decompression benefitted more from surgery than those who underwent single-level decompression.

CONCLUSION

Microsurgical bilateral decompression using unilateral laminotomy is an effective surgical option for lumbar spinal stenosis, even in high-risk patients with multilevel stenosis.

摘要

目的

我们描述了一项前瞻性队列研究,该研究调查了单侧椎板切开术双侧减压治疗腰椎管狭窄症的有效性,并评估了影响结果的因素。

方法

共有 165 例连续腰椎管狭窄症患者接受减压治疗。他们被分为 3 个年龄组:A(<65 岁)、B(65-75 岁)和 C(>75 岁)。进一步根据体质量指数(BMI)进行分类:BMI 1(<26)、BMI 2(26-30)和 BMI 3(>30)、麻醉相关危险因素(美国麻醉医师协会)和减压水平数。术后 1 周、3 个月和 1 年由独立观察者监测结果。评估以下参数:疼痛(视觉模拟评分和镇痛药消耗)、功能改善(神经性跛行结局评分)和行走能力,定义为行走距离 x 速度(跑步机)。

结果

术后 1 周时,85.9%的患者疼痛减轻,术前和术后镇痛药使用比较显示,非阿片类药物使用率下降 38%,阿片类药物使用率下降 74%,而非甾体抗炎药使用率增加 13%。术后 1 年时,83.9%的患者疼痛持续减轻,90.3%的患者神经性跛行结局评分增加,92.2%的患者行走能力改善。BMI>30 是疼痛减轻(P=0.012)和神经性跛行结局评分改善(P=0.019)的唯一负性预后因素。令人惊讶的是,与单节段减压相比,多节段减压的患者从手术中获益更多。

结论

单侧椎板切开术双侧减压是治疗腰椎管狭窄症的有效手术选择,即使是高危多节段狭窄患者也是如此。

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