Tanew A, Diem E, Lang I
Universitäts-Hautklinik, Wien.
Wien Klin Wochenschr. 1988 Feb 19;100(4):115-20.
Penicillins are the most commonly used antibiotics in dermatology owing to their bacteriocidal effect and the high responsiveness of most bacterial dermatoses to penicillin treatment. Although there is a wide range of adverse reactions to penicillins, severe complications are seen very rarely. We report on two cases of penicillin-induced acute interstitial nephritis and summarize the characteristic features of this serious adverse reaction to penicillin administration.
由于青霉素具有杀菌作用且大多数细菌性皮肤病对青霉素治疗反应良好,因此青霉素是皮肤科最常用的抗生素。尽管青霉素存在广泛的不良反应,但严重并发症却极为罕见。我们报告了两例青霉素诱发的急性间质性肾炎病例,并总结了这种青霉素给药严重不良反应的特征。