Service of Dermatology, Department of Internal Medicine, Faculty of Medicine, University of Antioquia and San Vicente Fundación Hospital, Medellín, Colombia.
Service of Dermatology, Department of Internal Medicine, Faculty of Medicine, University of Antioquia and San Vicente Fundación Hospital, Medellín, Colombia.
An Bras Dermatol. 2021 Mar-Apr;96(2):188-195. doi: 10.1016/j.abd.2020.06.014. Epub 2021 Feb 6.
Pyoderma gangrenosum associated to the use of cocaine/levamisole is a rare condition associated to their consumption. Cocaine use is frequent in Colombia, and the substance is contaminated with levamisole, an anthelmintic that increases the psychotropic effects and enhances its side effects. We present three clinical cases of patients with ulcerated lesions, in which the diagnosis was pyoderma gangrenosum secondary to the use of cocaine contaminated with levamisole. This called the attention of the health staff to investigate the abuse of substances in gangrenous pyoderma and also evidence that the interruption of consumption was the basis of management.
坏疽性脓皮病与可卡因/左旋咪唑的使用有关，这是一种罕见的与它们的使用相关的疾病。可卡因在哥伦比亚很常见，而且这种物质被左旋咪唑污染，左旋咪唑是一种驱虫剂，可增加精神活性作用并增强其副作用。我们介绍了三例患有溃疡性病变的患者的临床病例，其中诊断为继发于使用被左旋咪唑污染的可卡因的坏疽性脓皮病。这引起了卫生人员的注意，以调查坏疽性脓皮病中滥用物质的情况，并证明中断使用是治疗的基础。
