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[人类对接触产生蛋白质的微生物的免疫反应的性质]

[Nature of the human immune response to exposure to protein-producing microorganisms].

作者信息

Litovskaia A V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1988 Feb(2):71-5.

PMID:3364081
Abstract

The influence of the live culture and dried biomass of yeast-like fungi of the genus Candida on the characteristics of immune response in 1094 persons exposed to different concentrations of these fungi was studied. The subjects developed sensitization, manifested by immediate and cellular hypersensitivity reactions, as well as by disturbances in T-dependent and humoral immunity. The pattern of the detected changes depended on the concentration of the active factors and on the systemic condition of the subjects. Live fungal cells showed higher antigenic potency and were conducive to the development of allergic symptoms.

摘要

研究了念珠菌属酵母样真菌的活培养物和干生物质对1094名暴露于不同浓度这些真菌的人群免疫反应特征的影响。受试者出现了致敏反应,表现为即刻和细胞超敏反应,以及T细胞依赖性和体液免疫紊乱。检测到的变化模式取决于活性因子的浓度和受试者的全身状况。活真菌细胞显示出更高的抗原效力,且有利于过敏症状的发展。

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