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[利用念珠菌抗原检测速发型超敏反应时各种免疫反应效率的比较评估]

[Comparative evaluation of efficiency of various immunologic reactions with Candida antigens in detecting immediate hypersensitivity].

作者信息

Litovskaia A V, Mokeeva N V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 Sep(9):89-93.

PMID:2256409
Abstract

In the dynamic survey of 577 persons having had contacts with yeast-like fungi of the genus Candida the effectiveness of tests for the diagnosis of mycogenic sensitization was made with the use of a number of immunological methods. The basophil degranulation test was shown to have higher sensitivity and specificity in the detection of hypersensitivity to microbial strains used in the production processes of microbiological synthesis, while the use of polysaccharide antigens is more expedient in immunological reactions, such as the precipitation test with the finished product obtained by these processes and with C. albicans. Some prevalence of the level of sensitization in the presence of Candida carriership was established in persons having had contacts with these fungi.

摘要

在对577名曾接触念珠菌属酵母样真菌的人员进行的动态调查中,运用多种免疫学方法对诊断真菌致敏的检测方法的有效性进行了研究。结果表明,嗜碱性粒细胞脱颗粒试验在检测对微生物合成生产过程中使用的微生物菌株的超敏反应方面具有更高的敏感性和特异性,而在免疫反应中,如用这些过程获得的成品和白色念珠菌进行沉淀试验时,使用多糖抗原更为适宜。在接触过这些真菌的人员中,已确定在念珠菌携带情况下致敏水平存在一定普遍性。

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