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发病 6-24 小时内或起病时间不明的卒中症状患者的院前分诊准确性。

Prehospital Triage Accuracy in Patients With Stroke Symptoms Assessed Within 6 to 24 Hours or With an Unknown Time of Onset.

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden (T.A., A.B., C.S., E.E., M.V.M.).

Department of Neurology, Karolinska University Hospital, Stockholm, Sweden (A.B., C.S., E.E., M.V.M.).

出版信息

Stroke. 2021 Apr;52(4):1441-1445. doi: 10.1161/STROKEAHA.120.033676. Epub 2021 Mar 1.

Abstract

BACKGROUND AND PURPOSE

The Stockholm Stroke Triage System, implemented in 2017, identifies patients with high likelihood of large vessel occlusion (LVO) stroke. A previous report has shown Stockholm Stroke Triage System notably reduced time to endovascular thrombectomy (EVT). As the indication for EVT now includes patients up to 24 hours, we aimed to assess Stockholm Stroke Triage System triage accuracy for LVO stroke and EVT treatment for patients presenting late (within 6-24 hours or with an unknown onset), put in contrast to triage accuracy within 0 to 6 hours.

METHODS

Between October 2017 and October 2018, we included 2905 patients with suspected stroke, transported by priority 1 ground ambulance to a Stockholm Region hospital. Patients assessed 6 to 24 hours from last known well or with unknown onset were defined as late-presenting; those within <6 hours as early-presenting. Triage positivity was defined as transport to comprehensive stroke center because of suspected stroke, hemiparesis and high likelihood of EVT-eligible LVO per teleconsultation.

RESULTS

Overall triage accuracy was high in late-presenting patients (90.9% for LVO, 93.9% for EVT), with high specificity (95.7% for LVO, 94.5% for EVT), and low to moderate sensitivity (34.3% for LVO, 64.7% for EVT), with similar findings in the early-presenting group.

CONCLUSIONS

Our results may support using the Stockholm Stroke Triage System for primary stroke center bypass in patients assessed by ambulance up to 24 hours from time of last known well.

摘要

背景与目的

2017 年实施的斯德哥尔摩卒中分诊系统(Stockholm Stroke Triage System)可识别出发生大血管闭塞(LVO)卒中的可能性较高的患者。此前的一项报告表明,该系统显著缩短了血管内血栓切除术(EVT)的时间。由于现在 EVT 的适应证包括发病时间达 24 小时内的患者,我们旨在评估斯德哥尔摩卒中分诊系统对发病时间超过 6-24 小时或发病时间未知的 LVO 卒中患者的分诊准确性,并与发病时间在 0-6 小时内的患者进行对比。

方法

2017 年 10 月至 2018 年 10 月,我们纳入了 2905 例疑似卒中患者,这些患者通过优先级 1 的地面救护车被送往斯德哥尔摩地区的医院。发病时间在 6-24 小时或发病时间未知的患者被定义为晚期发病;发病时间在 6 小时内的患者为早期发病。分诊阳性定义为通过远程咨询怀疑卒中、偏瘫和极有可能进行 EVT 的 LVO 而被转运至综合卒中中心。

结果

晚期发病患者的总体分诊准确率较高(LVO 为 90.9%,EVT 为 93.9%),具有较高的特异性(LVO 为 95.7%,EVT 为 94.5%),敏感性较低(LVO 为 34.3%,EVT 为 64.7%),在早期发病患者中也有类似的发现。

结论

我们的结果可能支持在发病时间不超过 24 小时的情况下,使用斯德哥尔摩卒中分诊系统对通过救护车评估的患者进行初级卒中中心的直接转诊。

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