Department of Orthopaedics and Traumatology, 13621Prince of Wales Hospital, the Chinese University of Hong Kong, Shatin, HKSAR, China.
J Orthop Surg (Hong Kong). 2021 Jan-Apr;29(1):2309499021996842. doi: 10.1177/2309499021996842.
This study aims to investigate the long-term results of vascularized iliac bone grafting (VIBG) for osteonecrosis of the femoral head (ONFH). The primary outcome is the long-term survivorship of VIBG, using conversion to total hip arthroplasty as an end-point. Secondly, this study will also analyse the patient or disease factors influencing the long-term survivorship of VIBG.
Forty-two patients (50 hips) underwent VIBG for ONFH in our institute between September 1995 and November 2013. Only patients with a follow-up of at least 5 years were included. The risk factors, surgical complications and VIBG survivorship were recorded. The stage of ONFH was classified according to the Ficat staging of the pre-operative radiographs. VIBG was only performed to patients with ONFH of Ficat stage II and stage III. Patients with hip arthritis (Ficat stage IV) did not receive VIBG and thus excluded from the study. Long-term survivorship of VIBG is measured by conversion to total hip arthroplasty.
Twenty-eight hips (56%) had surviving VIBG for the duration of follow-up. The overall mean graft survival was 12.2 ± 7.8 years (0.4-24.0). Steroid and alcohol-induced osteonecrosis were more predominant in the graft-failure group, which had a hazard ratio of 2.33 and 2.07 respectively for graft failure ( = 0.047). In terms of complication, there was one case of groin wound infection which required surgical debridement.
At a long-term follow-up of 17 years, our results showed that VIBG is effective in treating patients with pre-collapse (Ficat Stage II) and early post-collapse (Ficat stage III) in ONFH. Alcoholics and patients with steroid are at a higher risk of graft failure, so VIBG should be performed cautiously in these patients. VIBG is an intermediate operation until osteoarthritis sets in, either by the progression of ONFH or natural degenerative change.
本研究旨在探讨带血管髂骨移植(VIBG)治疗股骨头坏死(ONFH)的长期疗效。主要结局指标为 VIBG 的长期存活率,以转换为全髋关节置换术作为终点。其次,本研究还将分析影响 VIBG 长期存活率的患者或疾病因素。
1995 年 9 月至 2013 年 11 月,我院对 42 例(50 髋)ONFH 患者行 VIBG。仅纳入随访时间至少 5 年的患者。记录了危险因素、手术并发症和 VIBG 存活率。根据术前 X 线片的 Ficat 分期对 ONFH 分期进行分类。仅对 Ficat 分期 II 期和 III 期的 ONFH 患者行 VIBG。髋关节炎(Ficat 分期 IV 期)患者不行 VIBG,因此排除在本研究之外。VIBG 的长期存活率通过转换为全髋关节置换术来衡量。
28 髋(56%)在随访期间 VIBG 存活。总体平均移植物存活率为 12.2±7.8 年(0.4-24.0)。类固醇和酒精性骨坏死在移植物失败组更为常见,其移植物失败的风险比分别为 2.33 和 2.07( = 0.047)。在并发症方面,有 1 例腹股沟伤口感染,需要手术清创。
在 17 年的长期随访中,我们的结果表明,VIBG 治疗塌陷前期(Ficat Ⅱ期)和早期塌陷后(Ficat Ⅲ期)ONFH 患者是有效的。酒精和类固醇患者移植物失败的风险较高,因此应谨慎对这些患者行 VIBG。VIBG 是一种中间手术,直到出现骨关节炎,无论是通过 ONFH 的进展还是自然退行性变化。