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手术髋关节脱位联合撞击植骨和植入髂骨瓣治疗股骨头坏死的临床疗效:中期回顾性研究。

Clinical Outcome of Surgical Hip Dislocation Combined with Impacting Bone Grafts and Implanting Iliac Bone Flaps in the Treatment of Osteonecrosis of the Femoral Head: A Mid-term Retrospective Study.

机构信息

The Department of Orthopedics, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Orthop Surg. 2022 Jun;14(6):1115-1125. doi: 10.1111/os.13295. Epub 2022 Apr 27.

Abstract

OBJECTIVE

To report the medium-term outcomes of surgical hip dislocation (SHD) combined with impacting bone grafts and implanting iliac bone flaps in the treatment of osteonecrosis of the femoral head (ONFH) and to define the indications for this treatment.

METHODS

This was a single-center retrospective study. In total, 64 patients (70 hips) with ONFH treated from January 2014 to December 2017 were included in this study. There were 51 males and 13 females aged 18-55 years with an average age of 32 years. All patients underwent surgery for SHD combined with impacting bone grafts and implanting iliac bone flaps. Preoperative and postoperative clinical outcomes were assessed. The clinical outcome was assessed using the Harris hip score (HHS) and the conversion rate of total hip arthroplasty (THA). Univariate and multivariate logistic regression analyses were performed to identify risk factors affecting the clinical outcome. Kaplan-Meier (K-M) analysis was applied to calculate the survival rate of the femoral head.

RESULTS

At the last follow-up (60 ± 15.08 months), the HHS was excellent for 41 hips, good for 17 hips, fair for three hips, and poor for nine hips. All nine hips with poor HHS underwent THA, including five in the first 2 years following the index surgery and four between three and 5 years. The conversion rate of total hip arthroplasty was 12.86%. Univariate and multivariate logistic regression analyses showed that the duration of hip pain and JIC classification type were significantly associated with clinical outcomes. Elderly age and advanced ONFH stage tended to lead to worse surgical outcomes. The overall survival rate of JIC classification type C1 and duration of pain ≤6 months was 98.1% and 97.8% at 72 months, respectively, as estimated by the Kaplan-Meier method.

CONCLUSION

Surgical hip dislocation combined with impacting bone grafts and implanting iliac bone flaps in the treatment of ONFH had a good mid-term clinical outcome, especially for patients with retention of the lateral column of the femoral head and hip pain less than 1 year.

摘要

目的

报告髋关节切开复位术(SHD)联合打压植骨及髂骨瓣植入治疗股骨头坏死(ONFH)的中期结果,并明确该治疗方法的适应证。

方法

这是一项单中心回顾性研究。共纳入 2014 年 1 月至 2017 年 12 月收治的 64 例(70 髋)ONFH 患者,其中男 51 例,女 13 例,年龄 18~55 岁,平均 32 岁。所有患者均接受 SHD 联合打压植骨及髂骨瓣植入术治疗。评估患者术前及术后的临床疗效。采用 Harris 髋关节评分(HHS)和全髋关节置换术(THA)的转化率评估临床疗效。采用单因素和多因素逻辑回归分析确定影响临床疗效的危险因素。采用 Kaplan-Meier(K-M)分析计算股骨头的生存率。

结果

末次随访(60±15.08 个月)时,41 髋 HHS 评估结果为优,17 髋为良,3 髋为可,9 髋为差。9 髋 HHS 评估差的患者均接受了 THA,其中 5 例发生在指数手术后的前 2 年,4 例发生在 3~5 年后。THA 转化率为 12.86%。单因素和多因素逻辑回归分析显示,髋关节疼痛持续时间和 JIC 分型与临床疗效显著相关。高龄和晚期 ONFH 患者的手术疗效往往较差。Kaplan-Meier 法估计 JIC 分型 C1 型和疼痛持续时间≤6 个月的患者在 72 个月时的总体生存率分别为 98.1%和 97.8%。

结论

髋关节切开复位术联合打压植骨及髂骨瓣植入治疗 ONFH 的中期临床疗效良好,尤其是对于保留股骨头外侧柱和髋关节疼痛持续时间<1 年的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5ca/9163981/6cafb0c0120d/OS-14-1115-g003.jpg

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