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儿童孤独症谱系障碍与癫痫:关于癫痫中孤独症发生的评论;其不同表现及相关诊断挑战。

Autism spectrum disorders and epilepsy in children: A commentary on the occurrence of autism in epilepsy; how it can present differently and the challenges associated with diagnosis.

机构信息

Developmental Epilepsy Clinic, Great Ormond Street Hospital, London WC1N3JH, UK.

Developmental Epilepsy Clinic, Great Ormond Street Hospital, London WC1N3JH, UK.

出版信息

Epilepsy Behav. 2021 Apr;117:107813. doi: 10.1016/j.yebeh.2021.107813. Epub 2021 Feb 26.

Abstract

Autism occurs more frequently in epilepsy, but is often not diagnosed. This could be due to a focus on medical issues, or because it presents differently from classic autism in its timing, phenotype, fluctuating profiles, and high level of comorbidity. Without a diagnosis, these children miss out on interventions that could modify outcome and their families and local teams will struggle to understand and support them. They also become a hidden group that does not participate in or benefit from research. This paper examined the issues and challenges of diagnosing autism in a population with a high-risk of epilepsy, drawing on more than 20 years' experience of a specialist multi-disciplinary Developmental Epilepsy Clinic (DEC).

摘要

自闭症在癫痫中更为常见,但往往未被诊断出来。这可能是由于专注于医学问题,或者因为它在时间、表型、波动特征和高共病率方面与经典自闭症表现不同。如果没有诊断,这些孩子就会错过可能改变结果的干预措施,他们的家庭和当地团队也将难以理解和支持他们。他们也成为一个不参与或受益于研究的隐藏群体。本文借鉴了一个专门的多学科发育性癫痫诊所(DEC)超过 20 年的经验,探讨了在癫痫高风险人群中诊断自闭症的问题和挑战。

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