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短暂性 Probst 束弥散受限：一种类似于临床轻度脑病的急性脑病，伴有可复发性胼胝体病变。

Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion.

机构信息

Division of Neurology, National Center for Child Health and Development, Japan.

Department of Radiology, National Center for Child Health and Development, Japan.

出版信息

Intern Med. 2021 Aug 15;60(16):2667-2670. doi: 10.2169/internalmedicine.6840-20. Epub 2021 Mar 1.

DOI:10.2169/internalmedicine.6840-20
PMID:33642486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8429303/
Abstract

Probst bundles are selectively seen in patients with agenesis of the corpus callosum (CC) and are thought to be homologous to the CC. We herein report a 19-year-old woman with partial agenesis of the CC. She developed acute encephalopathy during Bordetella pertussis infection. Brain magnetic resonance imaging (MRI) showed restricted diffusion of bilateral Probst bundles. She was treated with anti-epileptics and azithromycin and recovered with no neurological sequelae. Follow-up MRI showed the resolution of the diffusion abnormality. The characteristics of diffusion-weighted images on brain MRI and clinical course mimicked those in cases of clinically mild encephalopathy/encephalitis with reversible splenial lesion.

摘要

Probst 束在胼胝体发育不全（CC）患者中选择性出现，被认为与 CC 同源。我们在此报告一例 19 岁女性，部分 CC 发育不全。她在百日咳博德特氏菌感染期间发生急性脑病。脑磁共振成像（MRI）显示双侧 Probst 束弥散受限。她接受了抗癫痫药物和阿奇霉素治疗，无神经后遗症恢复。随访 MRI 显示弥散异常消退。脑 MRI 上弥散加权图像的特征和临床过程类似于临床轻度脑病/脑炎伴可逆性胼胝体病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/32a4d3722f97/1349-7235-60-2667-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/3654f606e0fc/1349-7235-60-2667-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/a170101c07ab/1349-7235-60-2667-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/32a4d3722f97/1349-7235-60-2667-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/3654f606e0fc/1349-7235-60-2667-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/a170101c07ab/1349-7235-60-2667-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a18b/8429303/32a4d3722f97/1349-7235-60-2667-g003.jpg

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Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis.扩散张量磁共振成像可显示胼胝体发育不全时半球纤维连接的改变。
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