Department of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Department of Nuclear Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Drug Discov Ther. 2021 Mar 10;15(1):35-38. doi: 10.5582/ddt.2020.03042. Epub 2021 Feb 27.
Lymph node tuberculosis is one of the most common forms of extrapulmonary tuberculosis worldwide. The study aimed to evaluate the role of positron emission tomography-computed tomography (PET-CT) in determining post-treatment response in lymph node tuberculosis. A PET-CT was done in all treatment naïve tubercular lymphadenitis adults at baseline and after six months of therapy. The post-treatment clinical response was compared with the metabolic response on PET-CT. Of the 25 patients with tubercular lymphadenitis, 9/25 patients showed a complete metabolic response (CMR) at six months, while 16 patients had a partial metabolic response (PMR). All patients with CMR had a good clinical response. However, discordance between clinical and PET findings was noticed in those with PMR. The role of PET-CT in evaluating post-treatment response in patients with tubercular lymphadenitis needs further evaluation with a larger sample size.
淋巴结结核是全球最常见的肺外结核形式之一。本研究旨在评估正电子发射断层扫描-计算机断层扫描（PET-CT）在确定淋巴结结核治疗后反应中的作用。所有初治结核性淋巴结炎成人患者在基线和治疗 6 个月时均行 PET-CT 检查。将治疗后临床反应与 PET-CT 的代谢反应进行比较。在 25 例结核性淋巴结炎患者中，9/25 例患者在 6 个月时显示完全代谢反应（CMR），而 16 例患者有部分代谢反应（PMR）。所有 CMR 患者均有良好的临床反应。然而，在 PMR 患者中，临床和 PET 结果之间存在差异。需要进一步评估 PET-CT 在评估结核性淋巴结炎患者治疗后反应中的作用，需要更大的样本量。
