Senthil Raja, Gangadharan Vadavattathu Padmanabhan, Ramachandran Nair Arun Visakh, Mahadevan Pushpa, Pratap Thara
Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi, Kerala, India.
Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India.
Indian J Nucl Med. 2020 Oct-Dec;35(4):362-363. doi: 10.4103/ijnm.IJNM_99_20. Epub 2020 Oct 21.
Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis.
骨佩吉特病恶变为肉瘤相对少见，约1%的此类患者会发生。虽然少数临床和影像学表现可能有助于预测恶变，但大多数表现是非特异性的。我们描述了1例声带癌合并骨佩吉特病伴肉瘤变的病例，其中F - 氟脱氧葡萄糖（FDG）正电子发射断层扫描 - 计算机断层扫描通过显示佩吉特骨病变区域FDG摄取增强以及FDG摄取阳性的成骨性肺转移，有助于准确诊断。
