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为什么阿尔茨海默病患者会消瘦?

Why are Alzheimer patients thin?

作者信息

Singh S, Mulley G P, Losowsky M S

机构信息

Department of Medicine, St James's Hospital, Leeds.

出版信息

Age Ageing. 1988 Jan;17(1):21-8. doi: 10.1093/ageing/17.1.21.

DOI:10.1093/ageing/17.1.21
PMID:3364307
Abstract

Nutritional assessments were performed in three groups of hospitalized elderly women comparable in age and mobility: a group with Alzheimer's disease (ALZ), a multi-infarct dementia group (MID) and a nondemented group (ND). We have shown that: ALZ patients lose weight and on average weigh 21% less than ND patients and 14% less than MID patients. This weight loss is not accounted for by any obvious deficit in food intake, or by malabsorption. Biochemical indices of nutrition are little different in the three groups. The reason for weight loss in ALZ remains uncertain.

摘要

对三组年龄和活动能力相当的住院老年女性进行了营养评估

一组患有阿尔茨海默病(ALZ),一组为多发性梗死性痴呆组(MID),另一组为非痴呆组(ND)。我们发现:ALZ患者体重减轻,平均比ND患者轻21%,比MID患者轻14%。这种体重减轻并非由食物摄入量的任何明显不足或吸收不良所致。三组的营养生化指标差异不大。ALZ患者体重减轻的原因仍不确定。

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