Division of Basic and Clinical Immunology, Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Front Immunol. 2021 Feb 11;12:634181. doi: 10.3389/fimmu.2021.634181. eCollection 2021.
Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies (PADs). Because they are also among the most common infections in healthy individuals, PADs are usually overlooked in these patients. Careful evaluation of the history, including frequency, chronicity, and presence of other infections, would help suspect PADs. This review will focus on infections in relatively common PADs, discussing diagnostic challenges, and some management strategies to prevent infections.
细菌呼吸道感染是原发性抗体缺陷症（PAD）的主要特征。由于它们也是健康个体中最常见的感染之一，因此在这些患者中通常会忽略 PAD。仔细评估病史，包括感染的频率、慢性程度和其他感染的存在，有助于怀疑 PAD。本文将重点讨论相对常见的 PAD 中的感染，讨论诊断挑战以及一些预防感染的管理策略。
