神经梅毒的脑单光子发射计算机断层扫描（SPECT）、正电子发射断层扫描（PET）及磁共振成像（MRI）影像学特征
Imaging Characteristics of Brain SPECT, PET, and MRI in Neurosyphilis.
作者信息
Choi Eun Kyoung, Kim Young Do, Jeong Hyeonseok, Chung Yong-An, Oh Jin Kyoung, Song In-Uk
机构信息
Department of Nuclear Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Department of Neurology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
出版信息
Nucl Med Mol Imaging. 2021 Feb;55(1):48-51. doi: 10.1007/s13139-021-00684-9. Epub 2021 Feb 6.
The incidence of neurosyphilis has declined since effective penicillin therapy against was introduced. However, the diagnosis of neurosyphilis early in the disease course is very important in order to select appropriate antibiotic therapy. We report brain MRI, SPECT with Tc-99m ECD, and PET with F-18 FDG findings before antibiotic therapy in a neurosyphilis patient with neurological symptoms. The cerebral cortices showed hypoperfusion with a patchy distribution on SPECT and foci with high signal intensity on MRI, suggesting ischemia. Brain PET showed areas with hypometabolism in the temporoparietal lobes bilaterally.
自从引入针对梅毒的有效青霉素治疗后，神经梅毒的发病率有所下降。然而，在疾病早期诊断神经梅毒对于选择合适的抗生素治疗非常重要。我们报告了一名有神经症状的神经梅毒患者在抗生素治疗前的脑部MRI、Tc-99m ECD单光子发射计算机断层扫描（SPECT）以及F-18氟代脱氧葡萄糖（FDG）正电子发射断层扫描（PET）结果。大脑皮层在SPECT上显示灌注不足，呈斑片状分布，在MRI上有高信号强度灶，提示缺血。脑部PET显示双侧颞顶叶存在代谢减低区域。
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