Sampliner R E, Steinbronn K, Garewal H S, Riddell R H
Department of Medicine, Veterans Administration Medical Center, Tucson, Arizona.
Am J Gastroenterol. 1988 May;83(5):510-2.
Seven of 45 patients with Barrett's esophagus prospectively followed with yearly endoscopy had histological evidence of squamous mucosa overlying Barrett's epithelium. This histological finding has previously been identified as a rare sequela of anti-reflux surgery. All seven patients had specialized columnar epithelium. No evidence of the overlying mucosa was recognized at endoscopy. Only one patient had previous anti-reflux surgery. During the observation interval, three patients had a decrease, and four had no change in the length of Barrett's epithelium. Squamous mucosa overlying columnar epithelium in Barrett's esophagus is not infrequent, and prior anti-reflux surgery is not a necessary precondition.
45例接受每年一次内镜检查的巴雷特食管患者中，有7例的组织学证据显示巴雷特上皮上方存在鳞状黏膜。这一组织学发现此前被认定为抗反流手术的罕见后遗症。所有7例患者均有特殊柱状上皮。内镜检查未发现上方黏膜的证据。只有1例患者曾接受抗反流手术。在观察期内，3例患者的巴雷特上皮长度缩短，4例无变化。巴雷特食管柱状上皮上方的鳞状黏膜并不罕见，既往抗反流手术并非必要前提条件。
