Li Yu-Nuo, Li Chun-Lei, Liu Zhao-Hui
Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China.
World J Clin Cases. 2021 Feb 16;9(5):1204-1209. doi: 10.12998/wjcc.v9.i5.1204.
Solitary fibrous tumors (SFTs) occurring in the parapharyngeal space are rare, and their final diagnosis depends on pathological and immunohistochemical analyses. Once the tumor is diagnosed, complete resection and regular postoperative follow-up are required.
A 40-year-old male patient with a right parotid gland mass discovered 8 years ago was admitted to hospital. The mass showed no tenderness or local skin redness. Imaging was carried out as the patient had stable vital signs and showed that the mass was a dumbbell-shaped tumor comprising a superficial tumor approximately 5 cm long and 3 cm wide in size that compressed the right parotid gland and a deep tumor located in the right parapharyngeal space approximately 4.5 cm long and 2.5 cm wide in size. Both tumors were connected in the middle. Prior to surgery, the tumors were considered to be parapharyngeal schwannomas. During surgical dissection, the tumors were found to be smooth and tough, without obvious adhesion to the surrounding tissues. The tumors were revealed to be a SFT following postoperative pathological analysis.
SFTs in the parapharyngeal space are rarely reported, and complete resection of such tumor is recommended. Adjuvant chemoradiotherapy is used in patients with extensive tumor invasion to lower the recurrence rate. Postoperative long-term follow-up is required.
发生于咽旁间隙的孤立性纤维瘤(SFTs)较为罕见,其最终诊断依赖于病理及免疫组化分析。一旦确诊肿瘤,需行完整切除并定期进行术后随访。
一名40岁男性患者因8年前发现右侧腮腺肿物入院。肿物无压痛,局部皮肤无发红。患者生命体征平稳,行影像学检查显示肿物为哑铃形肿瘤,包括一个长约5 cm、宽约3 cm的浅表肿瘤,压迫右侧腮腺,以及一个位于右侧咽旁间隙、长约4.5 cm、宽约2.5 cm的深部肿瘤。两个肿瘤在中间相连。术前,肿瘤被考虑为咽旁神经鞘瘤。手术解剖过程中,发现肿瘤质地光滑且坚韧,与周围组织无明显粘连。术后病理分析显示肿瘤为孤立性纤维瘤。
咽旁间隙的孤立性纤维瘤鲜有报道,建议对此类肿瘤进行完整切除。对于肿瘤广泛侵犯的患者,采用辅助放化疗以降低复发率。术后需要长期随访。