Zhao Hong-Guang, Zhang Ke-Wei, Hou Sen, Dai Yu-Yin, Xu Song-Bai
Department of Nuclear Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
World J Clin Cases. 2021 Feb 26;9(6):1353-1358. doi: 10.12998/wjcc.v9.i6.1353.
Epithelioid hemangioendothelioma (EHE) is an uncommon low-grade aggressive vascular tumor. It can occur in almost all locations, but is rarely encountered in bone.
We report a 23-year-old man who presented with left hip pain with no obvious cause. X-ray revealed bone destruction in the left femoral neck with sclerosis at the edges of the lesions. Magnetic resonance imaging (MRI) showed bone destruction in the medullary cavity of the left femoral head and neck. F-deoxyglucose-positron emission tomography/computed tomography (PET/CT) imaging showed bone destruction in the left ischium, acetabulum, and left femoral head neck, accompanied by increased radioactive uptake; the maximum standard uptake value was 4.2. Histopathologic examination revealed spindle-shaped mesenchymal tissue hyperplasia with scattered epithelioid cells. The patient underwent left femoral head replacement surgery. No signs of recurrence were observed as of the 18-mo follow-up.
The definitive diagnosis of femoral EHE can be established aided by the MRI and PET/CT findings.
上皮样血管内皮瘤（EHE）是一种罕见的低度侵袭性血管肿瘤。它几乎可发生于任何部位，但在骨骼中很少见。
我们报告一名23岁男性，无明显诱因出现左髋部疼痛。X线显示左股骨颈骨质破坏，病变边缘硬化。磁共振成像（MRI）显示左股骨头和颈髓腔内骨质破坏。F-脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（PET/CT）成像显示左坐骨、髋臼和左股骨头颈部骨质破坏，伴有放射性摄取增加；最大标准摄取值为4.2。组织病理学检查显示梭形间充质组织增生，散在分布上皮样细胞。该患者接受了左股骨头置换手术。截至18个月随访时，未观察到复发迹象。
股骨EHE的明确诊断可借助MRI和PET/CT检查结果得以确立。
