Koren Gideon, Ornoy Asher
Adelson faculty of medicine, Ariel University, Ariel, Israel.
Motherisk Israel, Clinical Pharmacology Unit, Shamir Hospital, Zrifin, Israel.
Glob Pediatr Health. 2021 Feb 15;8:2333794X21989556. doi: 10.1177/2333794X21989556. eCollection 2021.
Our objective was to estimate the likelihood of abnormal development among institutionalized children, addressing either the risk in general, or the risk for fetal alcohol spectrum disorder (FASD).
Narrative review of studies measuring developmental effects of these populations. We identified all systematic reviews and meta analyses dealing with the associations between institutionalization of children and their neurodevelopment in general, or between institunalization of children and their likelihood of suffering from FASD.
a) In a published meta-analysis the mean IQ/DQ was 84 among institutionalized children, as compared to 104 among children raised in families. Favorable caregiver-child ratios appeared to have a protective effect, whereas longer stays in institutions had a detrimental effect on IQ/b) A further meta- analysis has shown a positive impact of adoption on children's cognitive development with adopted children's displaying remarkably normal cognitive competence as compared to their non-adopted peers.c) The overall pooled prevalence was 6% (60 per 1,000, 95% CI 38-85) for full blown fetal alcohol syndrome (FAS), and 16.9% (95% CI 109-238 per 1,000) for the whole range of FASD.d) The estimated prevalence of FASD was 10-40 fold higher than the 7.7 per 1000 in the general population.
A large proportion of adopted institutionalized children may not follow a normal developmental trajectory. If not afflicted by FASD, there is a positive impact of adoption on children's cognitive development and in general they are comparable to their non- adopted peers.
我们的目标是评估机构收容儿童出现发育异常的可能性,探讨一般风险或胎儿酒精谱系障碍(FASD)风险。
对测量这些人群发育影响的研究进行叙述性综述。我们检索了所有关于儿童机构收容与其一般神经发育之间关联,或儿童机构收容与其患FASD可能性之间关联的系统评价和荟萃分析。
a)在一项已发表的荟萃分析中,机构收容儿童的平均智商/发育商为84,而家庭抚养儿童的平均智商/发育商为104。良好的照顾者与儿童比例似乎具有保护作用,而在机构中停留时间较长对智商有不利影响。b)另一项荟萃分析表明,收养对儿童认知发展有积极影响,与未被收养的同龄人相比,被收养儿童表现出明显正常的认知能力。c)全面胎儿酒精综合征(FAS)的总体合并患病率为6%(每1000人中有60例,95%可信区间为38 - 85),FASD的总体合并患病率为16.9%(每1000人中有109 - 238例,95%可信区间)。d)FASD的估计患病率比一般人群中每1000人7.7例的患病率高10 - 40倍。
很大一部分被收养的机构收容儿童可能无法遵循正常的发育轨迹。如果未患FASD,收养对儿童认知发展有积极影响,总体而言他们与未被收养的同龄人相当。