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Superiority of Gastrojejunostomy Over Endoscopic Stenting for Palliation of Malignant Gastric Outlet Obstruction.胃空肠吻合术优于内镜支架置入术治疗恶性胃出口梗阻的姑息治疗。
Clin Gastroenterol Hepatol. 2019 Jun;17(7):1295-1302.e1. doi: 10.1016/j.cgh.2018.10.042. Epub 2018 Oct 31.
2
Comparison of Treatment Outcomes of Endoscopic Stenting and Laparoscopic Gastrojejunostomy for Malignant Gastric Outlet Obstruction.内镜支架置入术与腹腔镜胃空肠吻合术治疗恶性胃出口梗阻的疗效比较
Am Surg. 2018 Jun 1;84(6):991-995.
3
Stent placement versus surgical palliation for adults with malignant gastric outlet obstruction.成人恶性胃出口梗阻患者的支架置入术与手术姑息治疗对比
Cochrane Database Syst Rev. 2018 May 30;5(5):CD012506. doi: 10.1002/14651858.CD012506.pub2.
4
Laparoscopic gastrojejunostomy for gastric outlet obstruction in patients with unresectable hepatopancreatobiliary cancers: A personal series and systematic review of the literature.腹腔镜胃空肠吻合术治疗不可切除的肝胆胰恶性肿瘤所致胃出口梗阻:个人系列及文献系统评价。
World J Gastroenterol. 2018 May 14;24(18):1978-1988. doi: 10.3748/wjg.v24.i18.1978.
5
Endoscopic duodenal stent versus surgical gastrojejunostomy for gastric outlet obstruction in patients with advanced pancreatic cancer.内镜十二指肠支架置入术与外科胃空肠吻合术治疗晚期胰腺癌患者胃出口梗阻的比较
Pancreatology. 2018 Jul;18(5):601-607. doi: 10.1016/j.pan.2018.04.015. Epub 2018 May 3.
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EUS-guided Gastrojejunostomy Versus Laparoscopic Gastrojejunostomy: An International Collaborative Study.超声内镜引导下胃空肠吻合术与腹腔镜胃空肠吻合术:一项国际合作研究。
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Laparoscopic Gastrojejunostomy for Patients with Unresectable Gastric Cancer with Gastric Outlet Obstruction.腹腔镜胃空肠吻合术治疗不可切除的伴有胃出口梗阻的胃癌患者
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A systematic review and meta-analysis comparing partial stomach partitioning gastrojejunostomy versus conventional gastrojejunostomy for malignant gastroduodenal obstruction.一项比较部分胃分隔式胃空肠吻合术与传统胃空肠吻合术治疗恶性胃十二指肠梗阻的系统评价和荟萃分析。
Langenbecks Arch Surg. 2016 Sep;401(6):777-85. doi: 10.1007/s00423-016-1470-8. Epub 2016 Jun 23.
9
Survival and clinical outcome after endoscopic duodenal stent placement for malignant gastric outlet obstruction: comparison of pancreatic cancer and nonpancreatic cancer.内镜下十二指肠支架置入术治疗恶性胃出口梗阻后的生存情况及临床结局:胰腺癌与非胰腺癌的比较
Gastrointest Endosc. 2015 Sep;82(3):460-8.e2. doi: 10.1016/j.gie.2015.01.026. Epub 2015 Apr 4.
10
Impact of carcinomatosis and ascites status on long-term outcomes of palliative treatment for patients with gastric outlet obstruction caused by unresectable gastric cancer: stent placement versus palliative gastrojejunostomy.癌性腹膜炎和腹水状态对无法切除的胃癌所致胃出口梗阻患者姑息治疗长期结局的影响:支架置入术与姑息性胃空肠吻合术的比较
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无法切除的癌症和胃出口梗阻患者的姑息性胃空肠吻合术:一项回顾性队列研究。

Palliative gastrojejunostomy in unresectable cancer and gastric outlet obstruction: a retrospective cohort study.

机构信息

Department of Surgery, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.

Department of Medical Education, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.

出版信息

Ann R Coll Surg Engl. 2021 Mar;103(3):197-202. doi: 10.1308/rcsann.2020.7016.

DOI:10.1308/rcsann.2020.7016
PMID:33645283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9158038/
Abstract

INTRODUCTION

Palliative gastrojejunostomy is a surgical technique that allows restoration of oral intake among patients with gastric outlet obstruction (GOO) caused by unresectable neoplasms. Research suggests standard treatment for malignant GOO should be laparoscopic gastrojejunostomy (LGJ). This study presents the clinical outcomes of palliative gastrojejunostomy and compares results from LGJ and open gastrojejunostomy (OGJ) at our centre.

METHODS

We performed a retrospective analysis on patients who underwent palliative gastrojejunostomy for GOO caused by unresectable neoplasms between 2008 and 2018. We included demographic variables, time to recover intestinal transit, time to recover oral intake, hospital stay, complications and global survival.

RESULTS

A total of 39 patients underwent palliative gastrojejunostomy (20 OGJ, 19 LGJ). Patients in the LGJ group recovered oral intake and intestinal transit faster than those in the OGJ group (3 vs 5 days, <0.05). There were no statistically significant differences in median operating time, hospital stay or postoperative complications between the two groups. No intraoperative complications occurred. The estimated global survival was 178 days, with no significant difference between the groups.

CONCLUSIONS

Palliative LGJ allows earlier restoration of oral intake and does not increase morbidity or mortality. Palliative LGJ should be considered the standard treatment for these patients.

摘要

介绍

姑息性胃空肠吻合术是一种手术技术,可使因无法切除的肿瘤引起的胃出口梗阻(GOO)患者恢复口服摄入。研究表明,恶性 GOO 的标准治疗应是腹腔镜胃空肠吻合术(LGJ)。本研究介绍了姑息性胃空肠吻合术的临床结果,并比较了我们中心 LGJ 和开腹胃空肠吻合术(OGJ)的结果。

方法

我们对 2008 年至 2018 年间因无法切除的肿瘤引起的 GOO 而行姑息性胃空肠吻合术的患者进行了回顾性分析。我们纳入了人口统计学变量、恢复肠道转运的时间、恢复口服摄入的时间、住院时间、并发症和总体生存率。

结果

共有 39 名患者接受了姑息性胃空肠吻合术(20 例 OGJ,19 例 LGJ)。LGJ 组患者恢复口服摄入和肠道转运的时间比 OGJ 组更快(3 天 vs 5 天,<0.05)。两组的中位手术时间、住院时间或术后并发症无统计学差异。术中无并发症发生。估计的总体生存率为 178 天,两组之间无显著差异。

结论

姑息性 LGJ 可更早恢复口服摄入,且不会增加发病率或死亡率。姑息性 LGJ 应被视为这些患者的标准治疗方法。