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眼眶淋巴瘤的首发表现:早期诊断的作用。

Initial Manifestation of Orbital Lymphomas: The Role of Early Diagnosis.

机构信息

Department of Diagnosis and Surgery, São Paulo State University (UNESP), Dental School of Araraquara, São Paulo, Brazil.

出版信息

J Craniofac Surg. 2021;32(5):e468-e470. doi: 10.1097/SCS.0000000000007409.

Abstract

Orbital lymphoma is a rare condition with non-specific and variable clinical course. This features are the main obstacle for diagnosis and treatment. A 43-year-old female patient complaining of vision loss and hemiface paresthesia, Proptosis was noted associated with an expansive lesion involving the right temporal lobe and orbital region. Craniotomy was performed to allow orbital decompression and anatomopathogical analysis. Final diagnosis was Burkitt Lymphoma. Patient evolved to death after seven days. A 40-year-old male patient complaining excessive tearing and sight disturbance. Proptosis on the right eye was noticed. Extra-conal expansive lesion was observed. Final diagnosis was mucosa-associated lymphoid tissue lymphoma. Radio and chemotherapy protocol was initiated. In a 3 year follow-up, there are no signs of recurrence or ocular/orbital impairment. Maxillofacial surgeons should be aware of the initial clinical presentation and always include lymphoid neoplasms as a differential diagnosis in cases which acute functional alterations are present.

摘要

眼眶淋巴瘤是一种罕见疾病,具有非特异性和多变的临床病程。这些特征是诊断和治疗的主要障碍。一位 43 岁的女性患者主诉视力丧失和半侧脸感觉异常,发现眼球突出,伴有累及右侧颞叶和眼眶区域的扩展性病变。进行了开颅手术以进行眼眶减压和解剖病理分析。最终诊断为伯基特淋巴瘤。患者在七天后死亡。一位 40 岁的男性患者主诉流泪过多和视力障碍。右眼眼球突出。观察到眶外扩展性病变。最终诊断为黏膜相关淋巴组织淋巴瘤。开始进行放射和化疗方案。在 3 年的随访中,没有复发或眼部/眼眶损伤的迹象。颌面外科医生应该了解最初的临床表现,并在出现急性功能改变的情况下,始终将淋巴肿瘤作为鉴别诊断的一种。

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