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使用 3D 打印柔性模具定制聚甲基丙烯酸甲酯植入物矫正面骨畸形的可行性。

Feasibility of Customised Polymethyl Methacrylate Implants Fabricated Using 3D Printed Flexible Moulds for Correction of Facial Skeletal Deformities.

机构信息

Department of Plastic, Aesthetic and Reconstructive Surgery, Medanta, The Medicity, Gurugram, India.

出版信息

J Craniofac Surg. 2021 Sep 1;32(6):1981-1985. doi: 10.1097/SCS.0000000000007383.

DOI:10.1097/SCS.0000000000007383
PMID:33645954
Abstract

INTRODUCTION

Use of patient specific Polymethyl methacrylate (PMMA) implants for the reconstruction of cranial defects has become a standard practice with excellent long-term results. However, for the reconstruction of midface and mandibular osseous defects other alloplastic materials are preferred but their use is limited due to high cost. This is a report of our experience with the use of low-cost patient specific PMMA implants fabricated using 3D printed moulds in the reconstruction of osseous defects involving different areas of the facial skeleton not limited to cranium.

METHODS

The 25 consecutive patients with craniofacial osseous defects who underwent reconstruction using customized PMMA implants were analyzed. All PMMA implants were fabricated intraoperatively with the use of 3D printed flexible moulds or templates.

RESULTS

A total of 34 implants were used in 25 consecutive patients. Out of 34 implants 25 were used for midface and mandibular osseous defects. Most common etiology was post-traumatic deformity (n = 19) followed by tumor (n = 3), craniofacial anomalies (n = 2) and post-craniotomy (n = 1). One patient out of 25 (n = 1) had postoperative implant exposure. The follow-up was ranged from 3 to 19 months with an average of 12 months. The aesthetic outcome was found to be good to excellent with mean visual analogue score of 4.08.

CONCLUSIONS

Polymethyl methacrylate implants fabricated intraoperatively using 3D printed moulds provide accurate and precise reconstruction at an exceptionally low cost. PMMA has an excellent moulding property with low infection rates. As shown in our study its application may be easily extended to all areas of the craniofacial skeleton.

摘要

简介

使用患者特异性聚甲基丙烯酸甲酯(PMMA)植入物来重建颅骨缺损已成为一种标准做法,其长期效果极佳。然而,对于中面部和下颌骨骨缺损的重建,其他同种异体材料是首选,但由于成本高,其使用受到限制。本文报告了我们使用低成本的患者特异性 PMMA 植入物的经验,这些植入物是使用 3D 打印模具在涉及面部骨骼不同区域的骨缺损重建中制造的,不限于颅骨。

方法

分析了 25 例连续接受定制 PMMA 植入物重建的颅面骨缺损患者。所有 PMMA 植入物均在术中使用 3D 打印的柔性模具或模板进行制造。

结果

25 例连续患者共使用 34 个植入物。在 34 个植入物中,有 25 个用于中面部和下颌骨骨缺损。最常见的病因是创伤后畸形(n=19),其次是肿瘤(n=3)、颅面畸形(n=2)和开颅术后(n=1)。25 例患者中有 1 例(n=1)术后出现植入物暴露。随访时间为 3 至 19 个月,平均 12 个月。美学结果良好至优秀,平均视觉模拟评分(VAS)为 4.08。

结论

使用 3D 打印模具术中制造的 PMMA 植入物可提供准确、精确的重建,成本极低。PMMA 具有极好的成型特性,感染率低。如我们的研究所示,其应用可轻松扩展到颅面骨骼的所有区域。

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